We will now walk through three case
studies of biodefense vaccines.
The first one will take us through
over 300 years of medical history
with the advent of variolation
to prevent smallpox.
The second study deals with
the use of the FDA animal
rule to expand the indication of
BioThrax, the anthrax vaccine,
from pre-exposure to
And lastly, we will cover a more
recent event that has mobilized
the biomedical community in
ways that we've never witnessed
before, the Ebola outbreak.
Let's begin with smallpox.
Smallpox is believed to have killed
more people than all wars combined.
It has devastated
mankind for centuries.
We are, indeed, fortunate
for the work of Edward Jenner
and the many scientists
that worked towards the ultimate
eradication of this scourge
Along with rinderpest, a
disease of ruminants, smallpox
is the only other disease
eradicated from this planet.