Good morning, everybody.
Thank you very much for attending
this talk about "Creating Animal
Models by Genetic Techniques".
My name is Emmanuel Gomas and
I've worked in the last 16 years
now in the field of
in particular, transgenic mice
and rats, both in academic labs,
but also in a private company.
In the last year I became
a consultant trying to help
and providing help to
laboratories and facilities
to improve their colony
management and facility management.
In the seminar series about
animal models embedded
in medical research,
it's important to have
a talk about transgenic animals,
because these transgenic animals
now are a big part of animal
models and may be one of the most
important part in animal models.
So it's very important to
understand where they come from,
why they are there, inside of
the evolution of animal models
through the ages.
But also it's important to know
how, technically, these animals are
engineered and the type
of genetic strategies
we can use in genetic engineering.
Also I will spend some
time on the latest
developments in genetic
in the last two or three years.
And I will finish
by speaking about some
applications of transgenic animals,
some state of the
art, and some points
in the future as a conclusion.
It's important to replace transgenic animal
models in the evolution of animal
models needs through the ages.
Because if we start in the early
steps of animal model experiments--
let's say with Claude Bernard or in
the Pasteur Institute as an early beginning
through today, there is a wide
range of use of animal models
and a huge evolution of
the use of animal models.