Behavioral phenotyping of mouse models of neuropsychiatric and neurodevelopmental disorders

Published on February 11, 2015   51 min

Other Talks in the Series: Animal Models in Biomedical Research

0:00
Hi. I am Jacqueline Crawley at the MIND Institute at the University of California, Davis in Sacramento in the US. And we'll be talking to you today about behavioral phenotyping of mouse models of neuropsychiatric and neurodevelopmental disorders, a field that our Behavioral Neuroscience Laboratory has been working on for over 30 years.
0:26
The fundamental question that you might ask is, why would one bother using an animal model in the first place? How do animal models contribute to biomedical research? Basically, we're designing research tools that will allow us to discover the functions of known and newly discovered genes, or signaling proteins, neurotransmitters, their receptors, anatomical pathways, epigenetic mechanisms, specifically to understand the causes of a human disease. If we have a good model, it then becomes a pre-clinical tool that tests potential treatments for their efficacy and safety.
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Behavioral phenotyping of mouse models of neuropsychiatric and neurodevelopmental disorders

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