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Printable Handouts
Navigable Slide Index
- Introduction
- Full depth articular cartilage structure
- Structural heterogeneity of cartilage
- Cartilage has a poor repair potential
- Lesion grades
- ACI: Autologous Chondrocyte Implantation
- Chondrocyte expansion
- Reseach on articular cartilage
- Cell division in cartilage
- Bovine MCP joint
- Progenitor isolation
- Differential adhesion assay
- Colony forming efficiency after adhesion to FN
- Integrin expression
- Expansion in culture from single colonies
- Expansion in culture: maintenance of phenotype
- Transfected developing chick wing bud
- Chondroprogenitor plasticity
- Summary
- Do stem/progenitors exist in mature tissue...
- Unilateral/unicompartmental O.A.of tibial plateau
- Human cartilage adheres to FN
- Human cartilage is clonogemic
- Mechanisms that regulate stem cells
- Notch/ligand expression
- Role of Notch1 in regulation stem cells population
- Notch cleavage and ligand binding
- Non-specific Notch inhibition abolishes clonality
- S2 inhibition by TIMP 3 inhibits CFE
- Mechanism of Notch1 activation
- Notch siRNA
- Non-specific activation by Jagged 1
- Human cartilage notch 1 expression
- Summary
- References
- References
- Acknowledgements
Topics Covered
- Cartilage repair
- Cartilage progenitor isolation and characterization
- Human articular cartilage progenitors
- The role of Delta/Notch signalling in progenitor proliferation
Talk Citation
Archer, C. (2007, October 1). Cartilage stem cells: tools for joint repair? [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 7, 2024, from https://doi.org/10.69645/DUUA8403.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Charles Archer has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Cartilage stem cells: tools for joint repair?
Published on October 1, 2007
17 min