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1. Introduction
2. Questions (1)
3. What are eosinophils? (1)
4. What are eosinophils? (2)
5. Eosinophil facts
6. The eosinophil
7. Tissue distribution of eosinophils in normal rats
8. Normal eosinophil morphology
9. Eosinophil electron micrograph
10. Eosinophil structure - primary granules
11. Eosinophil structure - secondary granules
12. Major Basic Protein (MBP)
13. Eosinophil Cationic Protein (ECP)
14. Eosinophil-Derived Neurotoxin (EDN)
15. Eosinophil Peroxidase (EPO)
16. Charcot-Leyden crystal protein
17. Charcot-Leyden crystals
18. Eosinophil secretion/degranulation
19. Eosinophil 'specific' granules
20. Eosinophils: surface components
21. Eosinophils: mediators
22. Eosinophil life cycle
23. Eosinophils differentiation and trafficking
24. Eosinophil moving from circulation into tissues
25. Eosinophil activation
26. Markedly activated eosinophil
27. Activated eosinophils have altered morphology
28. Questions (2)
29. Eosinophils: function
30. Eosinophil-mediated pathogenesis
31. Eosinophil: protective role against parasites
32. Eosinophil: pathogenic role in allergy
33. Eosinophils and apoptosis
34. Other functions?
35. Questions (3)
36. Eosinophilia
37. Eosinophilia: differential diagnosis
38. Eosinophilia and drug reactions
39. Eosinophilia and nonparasitic infectious diseases
40. Eosinophilia and protozoan infections
41. Eosinophilia and ectoparasites
42. Helminth causes of eosinophilia
43. Unexplained eosinophilia
44. Group of hypereosinophilic syndromes
45. Hypereosinophilic syndrome
46. HES subtypes
47. End-organ dysfunction in HES
48. HES: heart disease
49. FIP1L1/PDGFRA-associated CEL
50. Tissue fibrosis is a common sequela of F/P-HES
51. Familial eosinophilia
52. Summary
53. Acknowledgements

Topics Covered

• Eosinophil basics
• Eosinophil morphology
• Eosinophil function
• Eosinophil activation
• Eosinophilia
• Disorders associated with eosinophilia

Links

Series:

• Cells of the Innate Immune System

Categories:

• Biochemistry
• Cell Biology
• Clinical Practice
• Immunology

Therapeutic Areas:

• Immunology & Inflammation

Talk Citation

Nutman, T.B. (2012, June 11). Eosinophil biology and disorders associated with eosinophilia [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 11, 2025, from https://doi.org/10.69645/PLHE2030.
Export Citation (RIS)

Publication History

• Published on June 11, 2012

Financial Disclosures

• Dr. Thomas B. Nutman has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.