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Printable Handouts
Navigable Slide Index
- Introduction
- Genetics influence traits
- What is a quantitative trait?
- Quantitative and multifactorial inheritance
- Some history
- Some more history
- Basic biometric model (1)
- Basic biometric model (2)
- Basic biometric model (3)
- Identity states
- Identity coefficients
- Kinship coefficients
- Covariances for relatives (1)
- Covariances for relatives (2)
- Polygenic model (1)
- Polygenic model (2)
- Add environment
- Modeling environment/error
- Household effects models
- Variance component models
- Statistical process
- A gene x environment model
- Why? how?
- G x E model, mean
- G x E model, variance
- The San Antonio family heart study
- The data
- The questions
- The results, mean
- Gene ontology analysis
- The results, heritability
- GO BP results poly G x S
- GO-BP graph for sig poly G x S
- QTL mapping uses genotype data
- Genotyping
- QTL mapping
- Multivariate model
- SAFADS example
- Insulin Resistance Syndrome (IRS)
- Four trait heritability analysis
- QTL mapping process (1)
- QTL mapping process (2)
- FSI, BMI, leptin and DBP (1)
- FSI, BMI, leptin and DBP (2)
- Thanks
- References
Topics Covered
- Basic Biometric Model: single locus model, identity states and coefficients, Covariances for relatives, polygenic model
- Modeling environment/error
- Gene by environment interaction model and example
- QTL mapping model
- Multivariate model and example
Talk Citation
Bauman, L. (2012, May 22). Quantitative genetics and multifactorial inheritance [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 13, 2024, from https://doi.org/10.69645/RSBU3329.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Lara Bauman has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.