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1. Mononuclear phagocytes - origins, fates and functions
- Prof. Steffen Jung
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2. Transcription factors in macrophage differentiation
- Dr. Michael Sieweke
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3. Fetal macrophages
- Prof. Paul Martin
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4. The alveolar macrophage
- Dr. Ronald G. Crystal
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5. Airway macrophages in health and disease
- Prof. Tracy Hussell
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6. Intestinal macrophages - heterogeneity, origins and functions
- Prof. Allan Mowat
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7. Osteoclasts: what do they do and how do they do it?
- Prof. Steven L. Teitelbaum
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8. The biology of Fc receptors and complement receptors
- Prof. Steven Greenberg
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10. Tumour-associated macrophages
- Prof. Michele De Palma
- Dr. Mario Squadrito
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11. The recognition of pathogens by C-type lectins
- Prof. Gordon D. Brown
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12. Macrophage phagocytosis
- Prof. Joel Swanson
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13. Macrophage CD36 and atherosclerosis
- Dr. Maria Febbraio
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14. Toll-Like receptor signaling and the innate immune response
- Dr. Kate Fitzgerald
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15. Innate immune receptors as mediators of systemic inflammation and pathogenesis of malaria
- Prof. Ricardo Gazzinelli
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17. Triggering receptors expressed on myeloid cells (TREM)
- Dr. Daniel W. McVicar
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18. Influence of eicosanoid lipid mediators on macrophage innate immune functions
- Prof. Marc Peters-Golden
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19. Macrophage paired receptor interactions
- Prof. Neil Barclay
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20. Macrophage heterogeneity in atherosclerosis regression
- Prof. Edward Fisher
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21. Gaucher disease: from lysosomal storage to immunopathology
- Prof. Johannes M.F.G. Aerts
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22. Macrophage in asthma
- Prof. Douglas Robinson
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23. The macrophage mannose receptor
- Dr. Luisa Martinez-Pomares
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24. Myeloid-derived suppressor cells in cancer
- Prof. Dmitry Gabrilovich
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25. EGF-TM7 receptors
- Dr. Jörg Hamann
- Dr. Hsi-Hsien Lin
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26. Macrophages in helminth infection
- Prof. Judith Allen
- Archived Lectures *These may not cover the latest advances in the field
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27. Immunosuppressive mechanisms in myeloid cells
- Prof. Dmitry Gabrilovich
Printable Handouts
Navigable Slide Index
- Introduction
- The lung and the environment
- The alveoli
- Environmental stress
- The alveolar macrophage
- Alveolar macrophages (1)
- Bone marrow-derived cells
- Bronchoalveolar lavage
- Alveolar macrophages (2)
- Turnover of alveolar macrophages
- Normal functions of the alveolar macrophage
- Alveolar macrophages and host defenses (1)
- Alveolar macrophages and host defenses (2)
- Alveolar macrophages and host defenses (3)
- Alveolar macrophages and collateral damage
- Alveolar macrophages and disease
- Alveolar macrophages and lung infection
- Emphysema associated with HIV1+ smokers
- MMP expression in HIV1+ smokers
- MMP-1 levels in macrophages of HIV1+ individuals
- Up-regulated macrophage MMP gene expression
- Idiopathic pulmonary fibrosis
- Clinical features
- Alveolar macrophages photo micrograph
- Pathogenesis of the injury to the lung
- Macrophages and idiopathic pulmonary fibrosis
- Pulmonary alveolar proteinosis (1)
- Pulmonary alveolar proteinosis (2)
- Smoking-associated lung disease (1)
- Smoking and alveolar macrophages
- Cigarette smoking: changes in DNA methylation
- Alveolar macrophage transcriptome in smokers
- Study populations
- Macrophage genome-wide gene expression
- Gene expression comparison (1)
- Gene expression comparison (2)
- Gene expression comparison (3)
- Response variability of macrophages to smoking?
- Quantifying the extent of up- and down-regulation
- Index-AM
- Alveolar macrophage transcriptome
- Macrophage polarization programs
- M1 and M2 polarization
- M1 gene signature
- M2 gene signature
- Smoking-associated lung disease (2)
- Smoking & polarization programs of macrophages
- Nonsupervised hierarchical cluster analysis
- Comparison of M1 program suppression in AM
- M1-and M2-related protein expression: FACS
- M1 deactivation / partial M2-like reprogramming
- Polarization programs & development of COPD
- Reciprocal alteration of gene expression & COPD
- Smoking-induced modification of AM transcriptome
- Summary
Topics Covered
- Environmental stress and the lung
- Disorders and diseases of the lung
- Gene expression of macrophages
- Macrophage polarisation programs
- Smoking and alveolar macrophages
Links
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Talk Citation
Crystal, R.G. (2022, January 23). The alveolar macrophage [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 6, 2024, from https://doi.org/10.69645/KGFY2839.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Ronald G. Crystal has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.