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- Clinical Introduction
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1. Frontotemporal dementia
- Prof. Bruce Miller
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2. Parkinson disease
- Prof. Stanley Fahn
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3. Atypical parkinsonian syndromes
- Dr. David Burn
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4. Huntington's disease
- Prof. Roger Barker
- Neuroimaging
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5. Molecular brain imaging (PET) in diseases with dementia
- Prof. Karl Herholz
- Pathology, Genetic and Molecular Aspects (1)
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6. A molecular understanding of Alzheimer's disease
- Prof. John Hardy
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7. Neuropathology of neurodegenerative disorders
- Prof. Jillian Kril
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9. Ubiquitination and Alzheimer related disorders
- Prof. John Mayer
- Pathology, Genetic and Molecular Aspects (2)
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10. The molecular biology of Huntington's disease
- Prof. David C. Rubinsztein
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11. Metals, oxidative stress and neurodegeneration
- Prof. Ashley Bush
- Latest Developments in the Field
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12. Animal models of tauopathy
- Prof. David Westaway
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13. Parkinson's disease and transplants
- Prof. Roger Barker
- Archived Lectures *These may not cover the latest advances in the field
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14. Neuropathology of neurodegenerative disorders
- Prof. Jillian Kril
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15. Motor neurone disease: molecular basis
- Prof. Kevin Talbot
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16. Alzheimer's disease (AD)
- Prof. John Hodges
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17. Frontotemporal dementia syndromes
- Prof. John Hodges
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18. Motor neurone disease: clinical aspects
- Prof. Kevin Talbot
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19. Neuro-imaging in dementia: using MRI in routine work-up
- Prof. Philip Scheltens
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20. Prion diseases
- Prof. Pierluigi Gambetti
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21. Mitochondrial disorders and neurodegeneration
- Prof. Anthony Schapira
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23. Mutations in parkinsonian syndromes
- Dr. Andrew Singleton
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25. Frontotemporal dementia
- Prof. Bruce Miller
Printable Handouts
Navigable Slide Index
- Intro slide
- Outline
- A brief history (1)
- A brief history (2)
- A brief history (3)
- FTD/FTLD classification (1)
- FTD: overlaps
- FTD/FTLD classification (2)
- Causes of late onset dementia
- Causes of early onset dementia
- Levels of classification in FTD
- Frontal (behavioural) variant FTD (fvFTD)
- Typical fvFTD case: J.W. (1)
- Typical fvFTD case: J.W. (2)
- Typical fvFTD case: J.W. (3)
- Typical fvFTD case: J.W. (4)
- Typical fvFTD case: J.W. (5)
- Typical fvFTD case: J.W. (6)
- Neuropsychology in fvFTD
- Theory of mind (ToM)
- Performance on ToM and physical cartoons
- Emotion judgement
- Atrophy in fvFTD: orbitofrontal and medial cortex
- Semantic dementia (SD)
- Typical SD case: D.V. (1)
- Typical SD case: D.V. (2)
- Typical SD case: D.V. (3)
- Perirhinal cortex: a key region?
- VBM correlation with SD
- Brain basis of concept knowledge?
- Laterality
- Word-picture matching: faces vs. animals
- Progressive Non-Fluent Aphasia (PNFA) (1)
- Progressive Non-Fluent Aphasia (PNFA) (2)
- Distribution of atrophy: SD vs. PNFA
- FTD genetics: tau mutations
- FTD genetics: non-tau
- Pathology of FTD: histological subtypes
- Relationship between pathology/clinical syndrome
- Pathological basis of SD
- Histopathology in SD
- Survival from symptom onset
- Management
Topics Covered
- Clinical spectrum FTD
- Frontal or behavioural variant
- Semantic dementia
- Progressive non-fluent aphasia
- Disease overlap
- Genetic factors
- Epidemiological facts
- Neuropsychological methods and imaging diagnostics
- Pathological groupings of FTD
- Tau positive inclusions cases including Pick's disease, familial tauopathies and corticobasal degeneration
- Ubiquitin positive inclusions cases
- Multidisciplinary management of FTD
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Hodges, J. (2007, October 1). Frontotemporal dementia syndromes [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 14, 2024, from https://doi.org/10.69645/IHZP7026.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. John Hodges has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.