• Microbiota: Agents for Health and Disease
• 38 min
  1. Introduction to microbiota: agents for health and disease

  • Prof. B. Brett Finlay
• The Human Microbiota
• 86 min
  2. The human microbiome project

  • Prof. George Weinstock
• 56 min
  3. The human indigenous microbiota

  • Prof. David Relman
• 46 min
  4. Gut microbiota, chronic inflammation and metabolic syndrome

  • Prof. Andrew Gewirtz
• Microbiota and Disease
• 30 min
  5. Role of the microbiota in asthma

  • Prof. B. Brett Finlay
• 45 min
  6. Disappearing microbiota and human metabolic health

  • Prof. Martin Blaser
• 41 min
  7. The microbiota in the development of colitis due to Clostridium difficile infection

  • Dr. Vincent Young
• 55 min
  8. Gram+ bacterial microbiota - Yin & Yang of infectious disease

  • Prof. P. Patrick Cleary
• 50 min
  9. Salmonella diarrhea: contributions from the microbiota, the pathogen and the host

  • Prof. Dr. Wolf-Dietrich Hardt
• 45 min
  10. Paneth cells, antimicrobial peptides and the regulation of the intestinal microbiota

  • Dr. Nita Salzman
• 35 min
  11. Microbiota and oral disease

  • Prof. Dennis Cvitkovitch
• 34 min
  12. Microbiota and inflammatory bowel disease

  • Prof. Janet Jansson
• Host Responses
• 56 min
  13. The role of the enteric microbiota in T cell differentiation

  • Prof. Dan Littman
• 37 min
  14. Nod proteins in mucosal defense against bacteria: implications for Crohn's disease

  • Dr. Stephen Girardin
• 45 min
  15. Intestinal microbiota and the brain-gut axis

  • Prof. Stephen Collins
• 40 min
  16. Enteric pathogens-microbiota-host inter-kingdom chemical interactions

  • Prof. Vanessa Sperandio
• Preventatives and Therapeutics
• 42 min
  17. Probiotics

  • Dr. Gregor Reid
• Archived Lectures *These may not cover the latest advances in the field
• 58 min
  18. A new frontier in biology: deciphering the molecular language of symbiosis

  • Prof. Margaret McFall-Ngai
• 56 min
  19. Probiotics and prebiotics

  • Prof. Glenn Gibson

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. The gut as a functional ecosystem
3. Microflora of the stomach
4. Microflora of the small intestine
5. Microflora of the large intestine
6. Examples of gut disorders
7. Fermentation by colonic bacteria
8. Major components of the colonic ecosystem
9. "Normal" microbiota differs from patients'
10. A simplistic view of the gut flora
11. The diversity of the gut flora
12. What are probiotics?
13. Types of probiotics
14. Probiotics history (1)
15. Probiotics history (2)
16. Probiotic issues
17. Probiotics advertising
18. Science literature about probiotics
19. Some benefits of probiotics
20. Prebiotic - some definitions
21. Prebiotic - approaches (2004)
22. Prebiotics - definition (2010)
23. Prebiotics - general concept
24. Criteria for classifying a prebiotic
25. Prebiotic effects and the gut: testing
26. Prebiotic effects and the gut
27. Where do we find prebiotics?
28. All suggested prebiotics
29. Synbiotic definition
30. Combining probiotics and prebiotics
31. A new prebiotic GOS
32. Healthy human volunteer study on GOS
33. Effects of GOS on IBS sufferers
34. Effect of GOS on the colonic microflora of elderly
35. Efficacy of GOS in traveller's diarrhea
36. Effects of GOS on flatulence
37. Effects of GOS on bloating
38. Novel GOS - summary
39. Recent (pro)prebiotic in vivo trials
40. The human metabonome
41. Aspects
42. Thank you

Topics Covered

• The human large intestine is an intensively colonised area containing bacteria that are health promoting, as well as pathogenic
• This has led to functional food developments that fortify the former at the expense of the latter
• Probiotics have a long history of use in humans as live microbial feed additions
• In contrast, a prebiotic is a non digestible food ingredient that beneficially affects the host by targeting indigenous components thought to be positive
• Dietary carbohydrates, such as fibres are candidate prebiotics but most promise has been realised with oligosaccharides
• As prebiotics exploit non-viable food ingredients, their applicability in diets is wide ranging
• As gastrointestinal disorders are prevalent in terms of human health, both probiotics and prebiotics serve an important role in the prophylactic management of various acute and chronic gut derived conditions
• Examples include protection from gastroenteritis and some inflammatory conditions

Links

Series:

• Microbiota

Categories:

• Microbiology

Talk Citation

Publication History

• Published on September 27, 2011
• Archived on April 21, 2016

Financial Disclosures

• Prof. Glenn Gibson has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.