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- Advances in the Understanding of Etiology (I)
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1. Infection and autoimmunity: a two-way relationship
- Dr. Ricard Cervera
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2. Autoimmunity and atherosclerosis
- Prof. Johan Frostegard
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3. Endothelium and autoimmunity
- Prof. Pier Luigi Meroni
- Advances in the Understanding of Etiology (II)
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4. Prolactin has a pathogenic role in systemic lupus erythematosus
- Prof. Luis Jara-Quezada
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5. Sjögren's syndrome: current knowledge and future prospects
- Prof. Athanasios G. Tzioufas
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6. Genetic and environmental triggers of autoimmune thyroid diseases
- Prof. Yaron Tomer
- Advances in Pathogenesis and Clinical Manifestation
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8. Pathogenic mechanisms of autoantibodies: circulating and local antibodies that form immune complexes
- Dr. Luís Eduardo Coelho Andrade
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9. Pathogenic mechanisms of autoantibodies: antibodies to intracellular and membrane-bound antigens
- Dr. Luís Eduardo Coelho Andrade
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10. What causes primary biliary cholangitis?
- Dr. M. Eric Gershwin
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11. Capillaroscopy in autoimmune rheumatic diseases
- Prof. Maurizio Cutolo
- Advances in Diagnostic Methodologies (I)
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12. The past, present & future of ANA testing: history and challenges of ANA
- Prof. Marvin J. Fritzler
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13. The past, present & future of ANA testing: changing bandwidth and future of ANA
- Prof. Marvin J. Fritzler
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14. Diagnostic methods in autoimmunity
- Mr. Steven Binder
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15. Systemic lupus erythematosus: novel aspects of pathogenesis and treatment 1
- Prof. Chaim Putterman
- Dr. Noa Schwartz
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16. Systemic lupus erythematosus: novel aspects of pathogenesis and treatment 2
- Prof. Chaim Putterman
- Dr. Noa Schwartz
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17. Novel aspects of systemic sclerosis
- Prof. Gabriele Valentini
- Advances in Diagnostic Methodologies (II)
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18. An update on the multiple faces of celiac disease
- Prof. Aaron Lerner
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19. Protective autoantibodies
- Prof. Elias Toubi
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21. Rheumatic fever: a model of a post-infectious autoimmune disease
- Prof. Jorge Kalil
- Treatments of autoimmune diseases
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22. Intravenous immunoglobulins: clinical evidence
- Prof. Shaye Kivity
- Latest Developments in the Field
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23. Adjuvants and autoimmunity
- Dr. Eitan Israeli
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24. Antiphospholipid syndrome (APS): from pathogenesis to treatment
- Prof. Roger Levy
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25. Vitamin D and autoimmunity
- Dr. Shir Azrielant
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26. Pregnancy in rheumatic diseases
- Prof. Pier Luigi Meroni
- Archived Lectures *These may not cover the latest advances in the field
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27. Pathogenic mechanisms of autoantibodies
- Prof. Cees Kallenberg
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28. B lymphocytes on the frontline of autoimmunity
- Prof. Pierre Youinou
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29. Apoptotic cell clearance deficiency
- Prof. Martin Herrmann
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30. Auto-antibodies as predictors of autoimmune disease
- Dr. Nicola Bizzaro
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31. Innate immunity and natural autoantibodies
- Prof. Luc Mouthon
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32. Accelerated atherosclerosis in autoimmune rheumatic disease
- Dr. Andrea Doria
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33. Pregnancy in autoimmune rheumatic diseases
- Prof. Angela Tincani
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36. Immunologic mechanisms in systemic lupus erythematosus
- Prof. Kok-Yong Fong
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37. Osteoimmunology
- Prof. João Eurico Fonseca
- Ms. Joana Caetano-Lopes
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38. ANCA-associated systemic vasculitides
- Prof. Loic Guillevin
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39. The common origin for diverse autoimmune diseases
- Prof. Juan-Manuel Anaya
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40. Anti-cytokine therapy in rheumatoid arthritis
- Prof. Piercarlo Sarzi-Puttini
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41. Sjogren's syndrome: autoimmune epithelitis
- Prof. Haralampos Moutsopoulos
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42. Vitamin D and autoimmunity
- Dr. Howard Amital
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43. Intravenous immunoglobulins: myth and reality
- Prof. Zera Tellier
Printable Handouts
Navigable Slide Index
- Introduction
- Autoimmunity
- Etiology of autoimmune disease
- Induction of autoimmunity: mechanisms
- The spectrum of autoimmune diseases
- Organ-specific and non-organ-specific disorders
- Overlap of autoantibodies
- Stimulating anti-thyroid antibodies
- Placental transfer of stimulating anti-thyroid Abs
- The spectrum of autoimmune diseases (selection)
- Pathogenetic immune responses
- Role of auto-Abs in autoimmune diseases
- Anti-GBM, Goodpasture's syndrome (1)
- Anti-GBM, Goodpasture's syndrome (2)
- Anti-GBM disease membranes
- Type 2 reaction
- Anti-GBM, Goodpasture's syndrome (3)
- Type 3 reaction: formation of immune complexes
- SLE-ACR criteria
- Example of rash
- Class IV-S (A)
- Rise in anti-dsDNA and relapse
- Auto-Abs in lupus nephritis
- GBM-nucleosome-antibody interaction
- Auto-Abs to C1q: clinical associations
- Auto-Abs to C1q: relation to disease activity (1)
- Auto-Abs to C1q: relation to disease activity (2)
- Pathogenicity of anti-C1q in lupus nephritis (1)
- Pathogenicity of anti-C1q in lupus nephritis (2)
- ANCA-associated vasculitides
- Anti-neutrophil cytoplasmic Abs (ANCA)
- c-ANCA, anti-Pr3 and anti-MPO
- Pathogenetic pathways in the primary vasculitides
- ANCA-associated vasculitis: pauci-immune
- Clinical evidence for pathogenicity of ANCA (1)
- Clinical evidence for pathogenicity of ANCA (2)
- ANCA-induced PMN activation
- MPO-ANCA are pathogenic in vivo (1)
- MPO-ANCA are pathogenic in vivo (2)
- Are PR3-ANCA pathogenic in vivo?
- Nasal carriage of S. aureus and relapses of WG
- Are ANCA pathogenic?
- Pathogenic mechanisms of auto-Abs?
Topics Covered
- Loss of tolerance for "self"
- Immune response to "self"
- Self destruction
- Etiology of autoimmune diseases: endogenous and exogenous factors
- Mechanisms of autoimmunity
- The spectrum of autoimmune diseases
- Organ-specific and non-organ-specific disorders
- Overlap of autoantibodies
- Anti-thyroid antibodies
- Pathogenic immune responses
- Systemic autoimmune diseases
- Anti-GMB and Goodpasture's syndrome
- Anti-C1q
- ANCA-associated vasculitis
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Kallenberg, C. (2007, October 1). Pathogenic mechanisms of autoantibodies [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 22, 2024, from https://doi.org/10.69645/QVJS5465.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Cees Kallenberg has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.