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1. Introduction
2. General overview
3. Natural history of autoimmune diseases
4. Interpretation of auto-Ab in asymptomatic subject
5. Positive predictive value
6. Predictive value of auto-Abs
7. Disease with predictive auto-antibodies
8. Anti-dsDNA and SLE
9. Anti-nuclear antibodies and SLE
10. Auto-Abs present before the SLE clinical onset (1)
11. Auto-Abs present before the SLE clinical onset (2)
12. Anti-Ro/La Abs and Sjogren's syndrome
13. Anti-CCP, RF and RA
14. Anti-CCP before symptom onset
15. Specific auto-Abs precede the symptoms of RA (1)
16. Specific auto-Abs precede the symptoms of RA (2)
17. Anti-mitochondrial Abs and primary biliary cirrhosis
18. The Northeast England cohort
19. Anti-islet cell Abs and diabetes
20. Progression to diabetes vs. auto-Abs of IDDM
21. Gestational diabetes study
22. A study of IDDM prediction in children
23. Successful prediction of type 1 diabetes in children
24. Diabetes autoimmunity study in the young
25. Adrenal cortex Abs and Addison's disease
26. ACA and Addison's with autoimmune diseases
27. Anti-thyroid Abs and hypothyroidism
28. Anti-TPO Ab in pregnancy predictive of PPTD
29. Anti-tissue TG Abs and celiac disease
30. Study of childhood celiac disease
31. Anti-myelin Abs and multiple sclerosis
32. Kaplan-Meier estimates of the risk of ML by Abs
33. Anti S. cerevisiae Abs and Crohn's disease
34. Concluding remarks

Topics Covered

• Natural history of autoimmune diseases
• Predictive value of autoantibodies
• Anti-dsDNA antibodies and SLE
• Anti-nuclear antibodies and SLE
• Anti-Ro/La antibodies and Sjogren's syndrome
• Rheumatoid factor and anti-CCP antibodies in rheumatoid arthritis
• Anti-mitochondrial antibodies and primary biliary cirrhosis
• Autoantibodies in diabetes
• Adrenal cortex antibodies and Addison's disease
• Ant-thyroid antibodies and hypothyroidism
• Anti-tissue transglutaminase antibodies and celiac disease
• Autoantibodies and multiple sclerosis
• Anti-saccharomyces cerevisiae antibodies and Crohn's disease

Links

Series:

• Autoimmunity

Categories:

• Clinical Practice
• Immunology

Therapeutic Areas:

• Immunology & Inflammation

Talk Citation

Bizzaro, N. (2007, October 1). Auto-antibodies as predictors of autoimmune disease [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 3, 2024, from https://doi.org/10.69645/ZZEX8878.
Export Citation (RIS)

Publication History

• Published on October 1, 2007
• Archived on May 31, 2018

Financial Disclosures

• Dr. Nicola Bizzaro has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.