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- Advances in the Understanding of Etiology (I)
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1. Infection and autoimmunity: a two-way relationship
- Dr. Ricard Cervera
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2. Autoimmunity and atherosclerosis
- Prof. Johan Frostegard
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3. Endothelium and autoimmunity
- Prof. Pier Luigi Meroni
- Advances in the Understanding of Etiology (II)
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4. Prolactin has a pathogenic role in systemic lupus erythematosus
- Prof. Luis Jara-Quezada
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5. Sjögren's syndrome: current knowledge and future prospects
- Prof. Athanasios G. Tzioufas
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6. Genetic and environmental triggers of autoimmune thyroid diseases
- Prof. Yaron Tomer
- Advances in Pathogenesis and Clinical Manifestation
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8. Pathogenic mechanisms of autoantibodies: circulating and local antibodies that form immune complexes
- Dr. Luís Eduardo Coelho Andrade
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9. Pathogenic mechanisms of autoantibodies: antibodies to intracellular and membrane-bound antigens
- Dr. Luís Eduardo Coelho Andrade
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10. What causes primary biliary cholangitis?
- Dr. M. Eric Gershwin
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11. Capillaroscopy in autoimmune rheumatic diseases
- Prof. Maurizio Cutolo
- Advances in Diagnostic Methodologies (I)
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12. The past, present & future of ANA testing: history and challenges of ANA
- Prof. Marvin J. Fritzler
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13. The past, present & future of ANA testing: changing bandwidth and future of ANA
- Prof. Marvin J. Fritzler
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14. Diagnostic methods in autoimmunity
- Mr. Steven Binder
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15. Systemic lupus erythematosus: novel aspects of pathogenesis and treatment 1
- Prof. Chaim Putterman
- Dr. Noa Schwartz
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16. Systemic lupus erythematosus: novel aspects of pathogenesis and treatment 2
- Prof. Chaim Putterman
- Dr. Noa Schwartz
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17. Novel aspects of systemic sclerosis
- Prof. Gabriele Valentini
- Advances in Diagnostic Methodologies (II)
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18. An update on the multiple faces of celiac disease
- Prof. Aaron Lerner
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19. Protective autoantibodies
- Prof. Elias Toubi
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21. Rheumatic fever: a model of a post-infectious autoimmune disease
- Prof. Jorge Kalil
- Treatments of autoimmune diseases
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22. Intravenous immunoglobulins: clinical evidence
- Prof. Shaye Kivity
- Latest Developments in the Field
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23. Adjuvants and autoimmunity
- Dr. Eitan Israeli
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24. Antiphospholipid syndrome (APS): from pathogenesis to treatment
- Prof. Roger Levy
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25. Vitamin D and autoimmunity
- Dr. Shir Azrielant
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26. Pregnancy in rheumatic diseases
- Prof. Pier Luigi Meroni
- Archived Lectures *These may not cover the latest advances in the field
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27. Pathogenic mechanisms of autoantibodies
- Prof. Cees Kallenberg
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28. B lymphocytes on the frontline of autoimmunity
- Prof. Pierre Youinou
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29. Apoptotic cell clearance deficiency
- Prof. Martin Herrmann
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30. Auto-antibodies as predictors of autoimmune disease
- Dr. Nicola Bizzaro
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31. Innate immunity and natural autoantibodies
- Prof. Luc Mouthon
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32. Accelerated atherosclerosis in autoimmune rheumatic disease
- Dr. Andrea Doria
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33. Pregnancy in autoimmune rheumatic diseases
- Prof. Angela Tincani
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36. Immunologic mechanisms in systemic lupus erythematosus
- Prof. Kok-Yong Fong
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37. Osteoimmunology
- Prof. João Eurico Fonseca
- Ms. Joana Caetano-Lopes
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38. ANCA-associated systemic vasculitides
- Prof. Loic Guillevin
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39. The common origin for diverse autoimmune diseases
- Prof. Juan-Manuel Anaya
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40. Anti-cytokine therapy in rheumatoid arthritis
- Prof. Piercarlo Sarzi-Puttini
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41. Sjogren's syndrome: autoimmune epithelitis
- Prof. Haralampos Moutsopoulos
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42. Vitamin D and autoimmunity
- Dr. Howard Amital
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43. Intravenous immunoglobulins: myth and reality
- Prof. Zera Tellier
Printable Handouts
Navigable Slide Index
- Introduction
- What is autoimmunity?
- Female dominance in most autoimmune diseases
- Concept of tolerance
- Central tolerance
- Peripheral tolerance (1)
- Peripheral tolerance (2)
- Breakdown of tolerance
- What is needed for autoimmunity to occur?
- Autoimmune diseases (1)
- Autoimmune diseases (2)
- Susceptibility to autoimmune diseases
- Infection and initiation of autoimmunity (1)
- Initiation by bacterial infection
- Infection and initiation of autoimmunity (2)
- Initiation by viruses
- Infection and initiation of autoimmunity (3)
- Examples of important autoimmune diseases (1)
- Temporal arteritis
- Examples of important autoimmune diseases (2)
- Systemic lupus erythematosus (SLE)
- Risk of cardiovascular disease (CVD) in SLE
- Nested case control design
- Risk factors of CVD in SLE
- Examples of important autoimmune diseases (3)
- Atherosclerosis
- Atherosclerosis is an inflammatory disease
- Pro-inflammatory cytokines in atherosclerosis
- Plaque rupture leads to thrombosis
- The immune system in atherosclerosis (1)
- Heat shoch proteins
- Heat shock proteins (HSP) and atherosclerosis
- The immune system in atherosclerosis (2)
- Modification of LDL
- PAF and PAF-like lipids
- Oxidized LDL
- The immune system in atherosclerosis (3)
- Phosphorylcholine: epitope in OxLDL
- ELSA study design
- Study results
- Immunological differences between sexes
- Potential mechanisms for protective effects of aPC
- The immune system in atherosclerosis (4)
- Anti-phospholipid (aPL) antibodies
- Annexin A5
- Role of annexin-A5 in SLE-related CVDs (1)
- Role of annexin-A5 in SLE-related CVDs (2)
- Effect of IVIG on annexin A5 binding (1)
- Effect of IVIG on annexin A5 binding (2)
- Monoclonal aPL Ab inhibits annexin A5 binding
- How can aPL antibodies cause disease?
- Lupus anticoagulants
- Summary and conclusions
- Acknowledments
Topics Covered
- Autoimmunity
- High risk of atherosclerosis in autoimmune diseases, especially systemic lupus erythematosus (SLE)
- Antiphospholipid antibodies and atherosclerosis
- Association and risk factors for atherosclerosis and cardiovascular disease in SLE
- Autoimmune mechanisms in atherosclerosis in general
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Frostegard, J. (2007, October 1). Autoimmunity and atherosclerosis [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 4, 2024, from https://doi.org/10.69645/XGWW2685.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Johan Frostegard has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.