• Principles in Bacterial Pathogenesis
• 43 min
  1. The molecular basis of bacterial pathogenicity: an overview

  • Prof. B. Brett Finlay
• Gram Negative Pathogens
• 50 min
  2. Deciphering shigella invasion of epithelial cells

  • Prof. Philippe Sansonetti
• 43 min
  3. Legionella pneumophila: an intracellular pathogen of phagocytes

  • Dr. Craig Roy
• 57 min
  4. Cholera: a paradigm for understanding emergence, virulence and temporal patterns of disease

  • Prof. John Mekalanos
• 34 min
  5. Bordetella pertussis

  • Prof. Alison Weiss
• 37 min
  6. Salmonellae: molecular basis of infection

  • Prof. Samuel Miller
• 43 min
  7. The diversity of Escherichia coli infections

  • Prof. Michael Donnenberg
• 18 min
  8. Bacterial activation of epithelial signaling

  • Prof. Alice Prince
• 48 min
  9. Human pathogenic Yersinia species

  • Prof. James Bliska
• 32 min
  10. From CagA to CagA: the metamorphoses of the Helicobacter pylori's cytotoxin-associated gene A into the cancer-associated gene A

  • Dr. Antonello Covacci
• 46 min
  11. Dental pathogens

  • Prof. Ann Progulske-Fox
• 35 min
  12. Haemophilus

  • Prof. Robert Munson
• Gram Positive Pathogens
• 53 min
  13. The bacterial pathogen Listeria monocytogenes: an amazing multifaceted model

  • Prof. Pascale Cossart
• 42 min
  14. The war against extensively drug resistant Mycobacterium tuberculosis: intelligence acquisition

  • Prof. William Jacobs
• 48 min
  15. Molecular pathogenesis and prevention of Staphylococcus aureus infections

  • Prof. Olaf Schneewind
• 49 min
  16. Streptococcus pyogenes disease and molecular pathogenesis

  • Prof. P. Patrick Cleary
• Host Responses
• 29 min
  17. Microbial recognition and the immune response

  • Dr. Dana Philpott
• 40 min
  18. Enteric pathogens-microbiota-host inter-kingdom chemical interactions

  • Prof. Vanessa Sperandio
• 47 min
  19. Toll-like receptor signalling during infection and inflammation

  • Prof. Luke O'Neill
• 56 min
  20. The human indigenous microbiota

  • Prof. David Relman
• 53 min
  21. Human genetics of infectious diseases: the example of bacterial/mycobacterial infections

  • Dr. Laurent Abel
• 47 min
  22. Role of neutrophils in acute lung injury and repair

  • Prof. Gregory Downey
• Preventatives and Therapeutics
• 35 min
  23. Antibiotics and antibiotic resistance

  • Prof. Gerry Wright
• 36 min
  24. Vaccines: a health insurance of the 21st century

  • Prof. Rino Rappuoli
• 41 min
  25. Biodefense vaccines

  • Prof. James Nataro
• Archived Lectures *These may not cover the latest advances in the field
• 39 min
  26. Vaccines in the modern world

  • Prof. Gordon Dougan
• 39 min
  27. Bacterial infection of epithelial signaling

  • Prof. Alice Prince

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Vaccines will address challenges of 21st century
3. Aging society
4. Causes of increased average life expectancy
5. Increased life expectancy due to less diseases
6. Pasteur started the greatest revolution in history
7. Life expectancy is growing beyond prediction
8. HIV - example of the impact of infectious diseases
9. Vaccination is the most effective treatment
10. Future vaccination will be for all ages
11. New tech. increased vaccine targets and safety
12. Safety of vaccines increased in the 21st century
13. Vaccines developed following Pasteur principles
14. Safety concerns about crude preparations
15. Vaccines with safety concerns were discontinued
16. Increased vaccine safety
17. Types of novel technologies of vaccines
18. Meningococcal disease (1)
19. Meningococcal disease (2)
20. N. meningitidis has many serotypes
21. Glycoconjugation improves the immunogenicity
22. Conjugate vaccines for meningococcus C
23. A self antigen cannot be used for vaccination
24. No success for developing a vaccine for MenB
25. OMV was successful to eliminate epidemic in NZ
26. Genomics and "reverse vaccinology"
27. 3 main antigens included in a vaccine
28. A vaccine able to induce antibodies in vitro
29. Reverse vaccinology improves targeting
30. Vaccines are the response to antibiotic resistance
31. Many cancers can be prevented
32. New vaccines will address health of aging society
33. Emerging infections
34. The evolution of the H1 Hemagglutinin sequence
35. A vaccine against avian influenza, H5N1
36. MF59: established adjuvant in a licensed vaccine
37. Vaccinating with clade 1 H5N1 after clade 0
38. Memory T cells induced first, B are more abundant
39. The H5N1 pandemic prepared us to face H1N1
40. Poverty
41. Vaccines to address poverty
42. Addressing the gaps in vaccine development
43. Novartis Vaccines Institute for Global Health
44. Combination conjugate Salmonella vaccines
45. Vaccines in the 21st century

Topics Covered

• Major health challenges of the 21st Century
• Causes of increased life expectancy: conquest of infectious diseases
• Life expectancy is growing beyond prediction
• New technologies in the last 30 years
• Safety of vaccines
• Meningococcal disease
• Vaccines for Meningococcus C
• Meningococcus B
• Reverse vaccinology allows us to target many pathogens that were difficult or impossible before
• Prevention of cancers
• Vaccination and our aging society
• H5N1 vaccine
• Vaccines to address poverty
• Novartis Vaccines Institute for Global Health

Links

Series:

• Molecular Basis of Bacterial Infection

Categories:

• Clinical Practice
• Microbiology

Therapeutic Areas:

• Vaccines

Talk Citation

Publication History

• Published on August 31, 2011

Financial Disclosures

• Prof. Rino Rappuoli has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.