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1. Introduction
2. Designing small animal imaging facilities
3. What do you plan to image?
4. Imaging methods
5. What species to use
6. Regulatory oversight
7. Infectious and carcinogenic agents
8. Immunocompromised imaging (1)
9. What level of service?
10. Who will do the work?
11. UCLA imaging experiments: two roles
12. Animal handling training
13. Systems and personnel requirements
14. Planning the flow of the workspace
15. New Crump Imaging Center
16. PET-CT space
17. Vivarium
18. Support equipment
19. Computer network configuration
20. Database and image management
21. Web-based scheduling and image retrieval
22. Archiving and data retrieval
23. Operational considerations
24. Preclinical molecular imaging
25. Why use animals?
26. What is being imaged?
27. Experimental design issues
28. Glucose effects on FDG (1)
29. Glucose effects on FDG (2)
30. Probe uptake: anesthesia effects
31. Isoflurane effects on FDG uptake
32. Conventional anesthesia configuration
33. Anesthesia support
34. Anesthesia induction boxes
35. Immunocompromised imaging (2)
36. Staging mice
37. Temperature control
38. Brown fat uptake
39. Temperature effects in tumor bearing mice
40. Heating options
41. Intraperitoneal injections
42. Tail vein injections
43. Dynamic imaging prep
44. Blood sampling options
45. Tail blood sampling: tail 'poke'
46. Example images
47. Biodistribution and radiation dosimetry
48. Oncology imaging
49. D2 receptor ligand imaging using microPET
50. Perfusion and metabolism microPET images
51. microPET: oncology - PET-only
52. microPET: oncology - dual modality imaging
53. Dynamic imaging of FHBG
54. Fast temporal imaging: first past transit
55. Imaging cancer using PET-reporter gene & FHBG
56. Functional and morphological imaging
57. Adenovirus validation in lymph node metastasis
58. Optical imaging: bioluminescence/fluorescence
59. Fluorescent growth factor on implanted scaffold
60. Bone formation assessed using microCT
61. Getting it right
62. References and acknowledgements

Topics Covered

• Designing small animal imaging facilities
• Imaging methods
• Regulatory oversight
• Infectious and carcinogenic agents
• UCLA imaging experiments
• Animal handling training
• Systems and personnel requirements
• Planning the flow of the workspace
• Database and image management
• Archiving and data retrieval
• Operational considerations
• Preclinical molecular imaging: why use animals?
• Experimental design issues
• Anaesthesia
• Heating options
• Blood sampling
• Case studies
• Optical imaging
• Getting it right

Links

Series:

• Medical Imaging

Categories:

• Methods

Talk Citation

Publication History

• Published on April 1, 2010

Financial Disclosures

• Dr. David Stout has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.