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- Advances in the Understanding of Etiology (I)
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1. Infection and autoimmunity: a two-way relationship
- Dr. Ricard Cervera
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2. Autoimmunity and atherosclerosis
- Prof. Johan Frostegard
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3. Endothelium and autoimmunity
- Prof. Pier Luigi Meroni
- Advances in the Understanding of Etiology (II)
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4. Prolactin has a pathogenic role in systemic lupus erythematosus
- Prof. Luis Jara-Quezada
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5. Sjögren's syndrome: current knowledge and future prospects
- Prof. Athanasios G. Tzioufas
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6. Genetic and environmental triggers of autoimmune thyroid diseases
- Prof. Yaron Tomer
- Advances in Pathogenesis and Clinical Manifestation
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8. Pathogenic mechanisms of autoantibodies: circulating and local antibodies that form immune complexes
- Dr. Luís Eduardo Coelho Andrade
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9. Pathogenic mechanisms of autoantibodies: antibodies to intracellular and membrane-bound antigens
- Dr. Luís Eduardo Coelho Andrade
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10. What causes primary biliary cholangitis?
- Dr. M. Eric Gershwin
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11. Capillaroscopy in autoimmune rheumatic diseases
- Prof. Maurizio Cutolo
- Advances in Diagnostic Methodologies (I)
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12. The past, present & future of ANA testing: history and challenges of ANA
- Prof. Marvin J. Fritzler
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13. The past, present & future of ANA testing: changing bandwidth and future of ANA
- Prof. Marvin J. Fritzler
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14. Diagnostic methods in autoimmunity
- Mr. Steven Binder
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15. Systemic lupus erythematosus: novel aspects of pathogenesis and treatment 1
- Prof. Chaim Putterman
- Dr. Noa Schwartz
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16. Systemic lupus erythematosus: novel aspects of pathogenesis and treatment 2
- Prof. Chaim Putterman
- Dr. Noa Schwartz
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17. Novel aspects of systemic sclerosis
- Prof. Gabriele Valentini
- Advances in Diagnostic Methodologies (II)
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18. An update on the multiple faces of celiac disease
- Prof. Aaron Lerner
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19. Protective autoantibodies
- Prof. Elias Toubi
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21. Rheumatic fever: a model of a post-infectious autoimmune disease
- Prof. Jorge Kalil
- Treatments of autoimmune diseases
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22. Intravenous immunoglobulins: clinical evidence
- Prof. Shaye Kivity
- Latest Developments in the Field
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23. Adjuvants and autoimmunity
- Dr. Eitan Israeli
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24. Antiphospholipid syndrome (APS): from pathogenesis to treatment
- Prof. Roger Levy
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25. Vitamin D and autoimmunity
- Dr. Shir Azrielant
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26. Pregnancy in rheumatic diseases
- Prof. Pier Luigi Meroni
- Archived Lectures *These may not cover the latest advances in the field
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27. Pathogenic mechanisms of autoantibodies
- Prof. Cees Kallenberg
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28. B lymphocytes on the frontline of autoimmunity
- Prof. Pierre Youinou
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29. Apoptotic cell clearance deficiency
- Prof. Martin Herrmann
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30. Auto-antibodies as predictors of autoimmune disease
- Dr. Nicola Bizzaro
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31. Innate immunity and natural autoantibodies
- Prof. Luc Mouthon
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32. Accelerated atherosclerosis in autoimmune rheumatic disease
- Dr. Andrea Doria
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33. Pregnancy in autoimmune rheumatic diseases
- Prof. Angela Tincani
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36. Immunologic mechanisms in systemic lupus erythematosus
- Prof. Kok-Yong Fong
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37. Osteoimmunology
- Prof. João Eurico Fonseca
- Ms. Joana Caetano-Lopes
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38. ANCA-associated systemic vasculitides
- Prof. Loic Guillevin
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39. The common origin for diverse autoimmune diseases
- Prof. Juan-Manuel Anaya
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40. Anti-cytokine therapy in rheumatoid arthritis
- Prof. Piercarlo Sarzi-Puttini
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41. Sjogren's syndrome: autoimmune epithelitis
- Prof. Haralampos Moutsopoulos
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42. Vitamin D and autoimmunity
- Dr. Howard Amital
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43. Intravenous immunoglobulins: myth and reality
- Prof. Zera Tellier
Printable Handouts
Navigable Slide Index
- Introduction
- Outline
- History: fetal loss and LAC
- The use of anti-cardiolipin antigen
- GPL and past obstetric history
- International lupus congress NY 2002
- The primary antiphospholipid syndrome (pAPS)
- Causes of thromboses in SLE
- Congenital thrombophilias
- APS classification criteria (1)
- Sapporo 1998 conference
- APS classification criteria (2)
- APS classification criteria (3)
- LACs
- Anti-cardiolipin test (aCL)
- Autoimmunity
- Lupus and APS
- APS is related to LAC, aCL, anti-beta 2GP-I
- Frequency of aPL
- Systemic APS
- The Euro PL study
- Thrombotic microangiopathy (MAPS)
- Clinical presentations of APS
- The Lucio phenomenon
- Ginsberg study, blood 1992
- Targets: action
- Pathogenic mechanisms
- Pathogenesis data from animal models
- Passive and active transfer of APS
- Pathogenesis of obstetric APS (1)
- Pathogenesis of obstetric APS (2)
- CNS involvement in APS
- Snnedon's syndrome
- Neural injury pathogenesis in APS animal models
- Cardiopulmonary clinical presentation
- Importance of BP control in APS
- Impact of hypertension and hyperhomocysteinemia
- Management of APS
- Asymptomatic aPL
- Thrombosis treatment
- INR recommendations
- The importance of INR monitoring
- APS patients should maintain a monotonous diet
- Thrombocytopenia
- Obstetric management of APS
- Pregnancy: thrombosis and aPL
- Results from hospital university Pedro Ernesto
- Advantages and disadvantages of heparin
- Pregnancy and coumadin; clinical study (1)
- Pregnancy and coumadin; clinical study (2)
- Pregnancy and coumadin; clinical study (3)
- APS and preeclampsia
- HCQ in SLE pregnancy: clinical study
- Thrombocytopenia during pregnancy
- Catastrophic APS
- Alternative therapies
- Thromboses prevention
- Second hit
- Triggering factors
- Case study: 29 year old woman with pAPS
- Vaccination as an APS triggering factor
- Thromboembolism and antipsychotics
- Lung adenocarcinoma and thrombosis (1)
- Lung adenocarcinoma and thrombosis (2)
- The future of APS treatment
- APS: messages
- There is still a lot to learn
- Ethical issues
- Acknowledgements
- The 14'th international APS congress
Topics Covered
- History: fetal loss and LAC
- The use of anti-cardiolipin antigen
- GPL and past obstetric history
- The primary antiphospholipid syndrome (pAPS)
- Causes of thromboses in SLE
- Congenital thrombophilias
- APS classification criteria
- Anti-cardiolipin test (aCL)
- Autoimmunity
- Lupus and APS
- Thrombotic microangiopathy (MAPS)
- The Lucio phenomenon
- Pathogenesis
- CNS involvement in APS
- Snnedon's syndrome
- Neural injury pathogenesis in APS animal models
- Management of APS
- Asymptomatic aPL
- Thrombosis treatment
- INR recommendations
- Thrombocytopenia
- Obstetric management of APS
- Advantages and disadvantages of heparin
- Pregnancy and coumadin; clinical study
- APS and preeclampsia
- HCQ in SLE pregnancy: clinical study
- Thrombocytopenia during pregnancy
- Catastrophic APS
- Alternative therapies
- Vaccination as an APS triggering factor
- Thromboembolism and antipsychotics
- Lung adenocarcinoma and thrombosis
- The future of APS treatment
- Ethical issues
Talk Citation
Levy, R. (2010, February 9). Antiphospholipid syndrome (APS): from pathogenesis to treatment [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 8, 2024, from https://doi.org/10.69645/MBPV5986.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Roger Levy has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.