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Printable Handouts
Navigable Slide Index
- Introduction
- Cancer in developed vs. less developed countries
- Adult vs. childhood cancer
- Risk of cancer
- Cancer: the very basics
- Cancer cell biology
- What causes the mutations?
- Cancer roulette
- Cancer from an evolutionary point of view
- Evolutionary vs. proximate causes of diseases
- Diseases from an evolutionary perspective
- Darwinian medicine (1)
- Darwinian medicine (2)
- Limitations of adaptation by natural selection
- Evolutionary medicine and cancer: principle no. 1
- Design limitations/trade-offs
- Stem cells - a good idea?
- Stem cell behaviour and cancer risk (1)
- Stem cell behaviour and cancer risk (2)
- Evolutionary medicine and cancer: principle no. 2
- Clonal evolution of a cancer
- The process is not that simple
- Implications of cancer clones development
- Evolutionary medicine and cancer: principle no. 3
- Mismatches that result in cancer (1)
- Breast cancer is not a new disease
- Logic of breast cancer risk
- Mismatches that result in cancer (2)
- Evolutionary medicine and cancer: principle no. 4
- Ageing and cancer
- The cancer prescription
Topics Covered
- The prevalence of cancer: man vs. animals
- The proximal causes of cancer: mutations and genotoxic exposures
- Limitations of evolutionary adaptation by natural selection
- Vulnerability to cancer from an evolutionary perspective
- Lack of perfection in evolutionary 'engineering': faults/trade-offs
- Evolutionary adaptation 'has no eyes to the future': mismatches between genetics and lifestyle
- Natural selection will happen: evolution of robust cancer clones
- The only fitness test of 'natural selectability' in evolution is survival and reproductive success: cancer risk escalation in old age
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Talk Citation
Greaves, M. (2020, August 16). A darwinian eye view of cancer [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 3, 2024, from https://doi.org/10.69645/HINI2878.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Mel Greaves has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.