Registration for a live webinar on 'Neuroleptic malignant syndrome' is now open.
See webinar detailsWe noted you are experiencing viewing problems
-
Check with your IT department that JWPlatform, JWPlayer and Amazon AWS & CloudFront are not being blocked by your network. The relevant domains are *.jwplatform.com, *.jwpsrv.com, *.jwpcdn.com, jwpltx.com, jwpsrv.a.ssl.fastly.net, *.amazonaws.com and *.cloudfront.net. The relevant ports are 80 and 443.
-
Check the following talk links to see which ones work correctly:
Auto Mode
HTTP Progressive Download Send us your results from the above test links at access@hstalks.com and we will contact you with further advice on troubleshooting your viewing problems. -
No luck yet? More tips for troubleshooting viewing issues
-
Contact HST Support access@hstalks.com
-
Please review our troubleshooting guide for tips and advice on resolving your viewing problems.
-
For additional help, please don't hesitate to contact HST support access@hstalks.com
We hope you have enjoyed this limited-length demo
This is a limited length demo talk; you may
login or
review methods of
obtaining more access.
Printable Handouts
Navigable Slide Index
- Introduction
- Concept through proof of concept
- Epidemiological observations
- Methods of investigation in humans
- Mendelian and complex inheritance
- Mendelian genetics
- Invasive pneumococcal disease (IPD)
- Genetic disorders in the NF-KB signaling pathway
- IRAK-4/MyD88 deficiencies
- The genus Mycobacterium
- MSMD
- Gene mutations in MSMD
- IL12R-beta1 deficiency and tuberculosis (TB)
- Mendelian TB proportion in disseminated forms
- Investigation of common infectious diseases
- Tuberculosis and leprosy
- TB: individual variability in response to infection
- Complex TB inheritance: candidate genes
- Complex TB inheritance: major gene
- TB: genome-wide linkage screen
- Linkage to chromosome 8q12-q13
- Leprosy: response to M. leprae
- Leprosy clinical features
- Leprosy epidemiology
- Countries with increasing incidence
- Difficulties in investigating leprosy
- Leprosy per se
- Leprosy linkage analysis (1)
- Leprosy linkage analysis (2)
- Family-based association study
- Primary scan
- Results of the association study
- Exact replication in the same population (1)
- Exact replication in the same population (2)
- Case-control replication in Northern India (1)
- Case-control replication in Northern India (2)
- LTA+80 A allele effect on leprosy susceptibility
- Case-control replication in Brazil
- LTA+80 A allele effect in the Brazilian population
- Age at leprosy diagnosis
- Performing the analysis by age
- Concluding remarks on leprosy
- Continuous spectrum
- Genetic spectrum depends on age
- Acknowledgements (1)
- Acknowledgements (2)
- Some reviews in the subject
Topics Covered
- General strategy for investigating human genes in infectious diseases
- A continuous spectrum from Mendelian to complex predisposition
- Mendelian predisposition to invasive pneumococcal disease
- Mendelian predisposition to mycobacterial infections including tuberculosis
- Complex predisposition to tuberculosis and leprosy
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Abel, L. (2009, October 29). Human genetics of infectious diseases: the example of bacterial/mycobacterial infections [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 12, 2024, from https://doi.org/10.69645/HCXF6991.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Laurent Abel has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Human genetics of infectious diseases: the example of bacterial/mycobacterial infections
Published on October 29, 2009
53 min
A selection of talks on Microbiology
Hide