- Models of Investigation
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41 min
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44 min
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38 min
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62 min
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61 min
- Cell Types and Recruitment
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71 min
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51 min
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42 min
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63 min
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25 min
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61 min
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41 min
- Recognition and Signaling
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50 min
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42 min
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39 min
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44 min
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38 min
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41 min
- Modulation of Effector Responses
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22 min
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42 min
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54 min
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39 min
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38 min
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69 min
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42 min
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27 min
- Pathogen-Host Interactions
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46 min
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50 min
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56 min
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53 min
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34 min
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51 min
- Health and Disease
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39 min
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59 min
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33 min
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38 min
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36 min
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54 min
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49 min
- Archived Lectures *These may not cover the latest advances in the field
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73 min
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32 min
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51 min
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39 min
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63 min
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35 min
Topics Covered
- Understanding how receptors involved in the detection of infection (TLRs and NLRs) and inflammation (TNFRs) mediated their biological effects
- The activation of innate immune responses depends on recognition of infectious organisms (bacteria, fungi, viruses, etc.) by specialized pattern recognition receptors that include the large families of membrane-associated TLRs and cytosolic NLRs
- Signaling mechanisms used by TLRs and NLRs, as well as by TNFRs that respond to pro-inflammatory cytokines
- Their biological effects include the production of cytokines, chemokines, anti-microbial peptides and enzymes that generate inflammatory mediators and reactive oxygen
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Karin, M. (2009, May 31). Signaling by innate immune receptors [Video file]. In
The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 9, 2023, from
https://hstalks.com/bs/1295/.
Export Citation (RIS)
Publication History
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Published on May 31, 2009
Financial Disclosures
- Prof. Michael Karin has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.