Understanding how receptors involved in the detection of infection (TLRs and NLRs) and inflammation (TNFRs) mediated their biological effects
The activation of innate immune responses depends on recognition of infectious organisms (bacteria, fungi, viruses, etc.) by specialized pattern recognition receptors that include the large families of membrane-associated TLRs and cytosolic NLRs
Signaling mechanisms used by TLRs and NLRs, as well as by TNFRs that respond to pro-inflammatory cytokines
Their biological effects include the production of cytokines, chemokines, anti-microbial peptides and enzymes that generate inflammatory mediators and reactive oxygen
Karin, M. (2009, May 31). Signaling by innate immune receptors [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved May 16, 2021, from https://hstalks.com/bs/1295/.
Published on May 31, 2009
Prof. Michael Karin has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.