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1. Introduction
2. Subpopulations of B cells
3. The CD5+ marker in B cells
4. Two features of CD5+ B cells
5. B-1a, B-1b and B-2
6. Origine of B1 cells
7. Association with the BCR
8. Ontogenesis of B-cells
9. The issue of the marginal zone B cell
10. Two differentiation pathways of plasma cells
11. Cell interactions in germinal center
12. Lymphoid follicle
13. B cells multifaceted activity
14. Recombination activating genes
15. MRL / lpr model
16. Effects of B cells on dendritic cells
17. Antigen presenting cells
18. Cellular and antibody responses
19. Production of cytokines
20. Tolerance breakdown
21. B-cell tolerance
22. Mouse models for anergy
23. Modulation of the BCR threshold
24. CD19 and CD21
25. RAG1+, RAG2+
26. Tuning the message
27. Lipid rafts
28. The kinetics of lipid rafts phenomenon
29. B cell activating factor of the TNF family
30. Serum level of BAFF in disease
31. Epithelial cells produce BAFF
32. CD5 gene
33. The usage of CD5-E1B is restricted to B cells
34. The synthesis of the truncated CD5+ protein
35. Conventional/alternative exon 1
36. In summary
37. Aknowledgements

Topics Covered

• Subpopulations of B cells
• CD5-positive B cells
• Marginal zone B cells
• Follicular B cells
• Pathogenic B cells
• Cytokine-producing B cells
• B cells and tolerance
• BCR co-receptor molecules
• Lipid rafts
• BAFF in autoimmunity
• The CD5 molecule in tolerance

Links

Series:

• Autoimmunity

Categories:

• Immunology

Therapeutic Areas:

• Immunology & Inflammation

Talk Citation

Publication History

• Published on October 1, 2007
• Archived on May 31, 2018

Financial Disclosures

• Prof. Pierre Youinou has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.