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1. Introduction
2. Diversity of animals
3. How does diversity arise?
4. Development and generation of new morphologies
5. From egg to organism
6. Use of model species in genetic studies
7. Drosophila melanogaster (fruit fly)
8. Normal fly vs. Ubx mutant
9. Homeosis and homeotic
10. Homeotic (Hox) genes
11. Protein distribution of 4 Hox genes in a fly embryo
12. Phenotype of Hox genes mutants
13. Ubx expression pattern in Drosophila (1)
14. Ubx expression pattern in Drosophila (2)
15. Changes in Ubx expression in a mutant
16. The central dogma
17. Activity of regulatory DNA
18. Conservation of homeotic genes
19. Ubx mutants resemble other insects (1)
20. Ubx mutants resemble other insects (2)
21. Phylogenetic tree of insects
22. Wings evolution in insects
23. Three hyphotheses for Ubx evolution in insects
24. Ubx expression pattern in different insects
25. Ubx expression pattern in butterfly wings
26. Forewings differ from hindwings in insects
27. Manipulation of Ubx expression in butterflies
28. Change in Ubx targets (1)
29. Change in Ubx targets (2)
30. Crustaceans
31. Artemia
32. Homeotic genes in Artemia
33. Ubx expression pattern in Artemia
34. Triops
35. Crayfish
36. Appendages morphology in mysid shrimp
37. Scheme of Crustaceans diversity
38. Possibility of homeotic transformation
39. Ubx expression pattern in Mysidium
40. Lobster
41. Periclimenes
42. Appendages evolution and Ubx expression
43. Parhyale hawaiensis (beach scud)
44. Characteristics of Parhyale hawaiensis
45. Parhyale development
46. Parhyale Hox expression domains (1)
47. Parhyale Hox expression domains (2)
48. Changing Ubx expression domains in Parhyale
49. Wild-type vs. siRNA knockdown of Ubx
50. Knockdown of Ubx gene using siRNA (1)
51. Knockdown of Ubx gene using siRNA (2)
52. Changing Ubx expression in Parhyale: conclusion
53. What is responsible for the shift in Ubx expression
54. Control of Hox genes expression in flies
55. Hb represses Ubx
56. Trans changes
57. Cis changes
58. Understanding Ubx expression in Crustaceans
59. Transformation of Parhyale
60. Understanding Ubx evolution (1)
61. Understanding Ubx evolution (2)
62. Results if "trans" evolution is correct
63. Results if "cis" evolution is correct
64. Hox genes and diversity: conclusion
65. Potential role of Hox genes in vertebrates evolution
66. Summary
67. Acknowledgements (1)
68. Acknowledgements (2)

Topics Covered

• Role of homeotic (Hox) genes in morphological evolution
• Arthropod evolution
• Crustacean appendages
• The role of gene regulation in evolution

Links

Series:

• The Legacy of Drosophila Genetics

Categories:

• Genetics & Epigenetics
• Reproduction & Development

Talk Citation

Publication History

• Published on September 29, 2008
• Reviewed on May 31, 2018

Financial Disclosures

• Prof. Nipam Patel has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.