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Printable Handouts
Navigable Slide Index
- Introduction
- Content
- Hospital admission
- Meta-analysis results for congenital malformation
- Comparison of ART infants/singletons with those conceived naturally: meta-analysis of 57 studies
- Comparison of ART twins/multiples with those conceived naturally: meta-analysis of 57 studies
- Comparison of ART infants/singletons with those conceived naturally: meta analysis of 45 studies
- Comparison of ART twins/multiples with those conceived naturally: meta analysis of 45 studies
- Comparison of the IVF/ICSI children with those conceived naturally: meta-analysis of 56 studies
- Comparison of the IVF/ICSI children with those conceived naturally: meta-analysis of 7 studies
- Comparisons between IVF/ICSI children vs. naturally & ICSI children vs. IVF children
- Subgroups of conditions
- Respiratory disease in all children (singletons & multiples)
- Respiratory disease in singletons (1)
- Respiratory disease in singletons (2)
- Respiratory disease in multiples
- Genitorurinary diseases in all children (singletons & multiples)
- Parental subfertility and hypospadias
- Congenital heart defects in IVF/ICSI pregnancy: meta-analysis of 8 studies
- Cardiovascular disease and ART offspring
- Neurodevelopmental outcomes
- Attention-deficit hyperactivity disorder (ADHD) in all children
- Autism spectrum disorders
- Epilepsy in all children
- Epilepsy in singletons and multiples
- Cerebral palsy
- Neonatal Intensive Care Unit (NICU) admission
- Other perinatal outcomes
- Preterm birth at <37 weeks' gestation
- Birth weight
- Perinatal mortality
- Small for gestational age
- Cancer risk in children born after ART - answers from research in a place near you
- Childhood cancer
- What we found
- In summary
- Final message (for fertility specialists!)
Topics Covered
- Health concerns regarding children conceived with ART
- Different types of ART covered (e.g. fresh frozen ICSI)
- Hospital admission rates
- Congenital anomalies
- Respiratory illnesses and other outcomes
- Neurological and neurodevelopmental outcomes
- Neonatal outcomes
- Cancer risk
- Implications for families and fertility practitioners
Links
Categories:
Therapeutic Areas:
Talk Citation
Sutcliffe, A. (2020, August 31). Outcomes in children born after assisted reproductive technology [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 6, 2024, from https://doi.org/10.69645/YHLQ8057.Export Citation (RIS)
Publication History
Financial Disclosures
- There are no commercial/financial matters to disclose.
A selection of talks on Clinical Practice
Transcript
Please wait while the transcript is being prepared...
0:00
Hello everybody, I'm Professor Alastair Sutcliffe.
I am a children's doctor.
Through and through I'm based at the University College London,
Great Ormond Street Institute of Child Health.
I'm giving this presentation because over
the past 25 plus years I've conducted
studies regarding the health of children born after what I call ART,
Assisted Reproductive Therapies or
Assisted Reproductive Technologies depending on your inclination.
During that field, for which I was a relative pioneer,
there has been, during that period,
considerable increase in studies giving indications as to
what the health issues may or may not
be with these children that had been conceived with this,
one might call it, unnatural way of reproducing full stop.
I'm actually quite fond of quoting somebody that I met,
who's quoted in my book,
"IVF children: The First Generation" which is a little out of date now,
who used to pick me up from a city called Nottingham in the middle of England,
and that was Dave.
Dave was a taxi driver,
and he's quoted in my book and has become famous
throughout the world because of his insight.
He was asking me what I was doing there and he said,
"What are you doing in Nottingham dock?"
This was in the days when I was actually going assessing children after
a type of IVF called intracytoplasmic sperm injection or ICSI,
and I explained then he said,
"It's hardly a Darwinian way of reproducing",
which I thought was quite a succinct comment.
What about this presentation you're going to listen to?
Its fairly fact heavy,
but I would ask you to use the slides merely as references.
They're pretty contemporaneous in terms of the effort to bring
together the messages from a variety of studies across the world literature.