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- Statistical Genetics of Complex Diseases
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1. Population genetics considerations
- Prof. Nan Laird
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2. Gene-by-environment interaction: study designs and analytical methods
- Prof. L. Adrienne Cupples
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3. Analysis of SNP haplotypes
- Prof. Lyle Palmer
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4. Statistical issues in epidemiological studies of gene-environment interaction
- Dr. Peter Kraft
- Prof. Donna Spiegelman
- Molecular Epidemiology of Pulmonary Diseases
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5. Molecular epidemiology of lung cancer
- Prof. David Christiani
- Autoimmune Diffuse Connective Tissue Diseases
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7. Environmental scleroderma: the evidence for putative triggers
- Prof. Maureen Mayes
- Drug-Induced Disease
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8. Drug-induced lupus
- Prof. Evelyn Hess
- Archived Lectures *These may not cover the latest advances in the field
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9. Biomarkers of exposure
- Prof. Thomas Smith
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10. GIS and spatial statistics
- Prof. Louise Ryan
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11. Gene-by-environment interactions in COPD
- Prof. Edwin Silverman
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14. Indians, twins and scleroderma: genetic and genomic studies
- Prof. Frank Arnett
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15. Gene by environment interaction in asthma
- Prof. Scott Weiss
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16. Molecular epidemiology of lung cancer
- Prof. David Christiani
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18. Infectious environmental factors and systemic lupus erythematosus
- Prof. Judith James
Printable Handouts
Navigable Slide Index
- Introduction
- Overview
- Autoimmune diseases (1)
- Autoimmune diseases (2)
- Genes and autoimmune disease (1)
- Genes and autoimmune disease (2)
- Genes and autoimmune disease (3)
- What do we know about Lupus?
- Incidence of SLE among woman by age (1)
- Incidence of SLE among woman by age (2)
- Pathogenesis of Lupus
- Causes of Lupus (1)
- Causes of Lupus (2)
- Number of Lupus publications by year and type
- Environment and Lupus
- Environment influences on risk of developing Lupus
- Occupational risk factors silica dust
- Silica and Lupus: descriptive and cohort studies
- Silica dust and Lupus: case control studies
- Silica dust and Lupus: clinical issues
- Silica dust and Lupus: experimental studies
- Silica dust and Lupus: other mechanistic issues
- Solvents
- Solvents and Lupus
- Smoking and hair dyes - rationale
- Smoking and Lupus
- Hair dyes and Lupus
- Potential gene-environment interactions
- Suggestive gene-environment interactions
- What is ultraviolet radiation?
- Sun exposure and Lupus
- Sun exposure and Lupus: case control studies
- Environmental influences on severity of Lupus
- Measures of disease severity or progression
- Disease activity and disease damage
- What about smoking?
- Hair dyes and disease severity
- Environmental pollutants and Lupus
- Environmental pollutants: air
- Environmental pollutants: air and water
- Environmental pollutants: food
- Mercury exposure and Lupus
- Conclusions: studying "environment" is worthwhile
- Conclusions: gene-environment interactions
- Conclusions: interdisciplinary exchange
- Understanding the etiology of Lupus
- References (1)
- References (2)
- References (3)
- References (4)
- References (5)
- References (6)
- References (7)
- References (8)
Topics Covered
- Role of genetic susceptibility in the etiology of systemic lupus erythematosus (SLE)
- Demographic risk factors for SLE
- Epidemiologic and experimental research on occupational exposures (respirable silica dust and solvents) and risk of developing SLE
- "Lifestyle" factors (smoking, use of hair dyes) and risk of developing SLE
- Ultraviolet radiation and risk of developing SLE
- Research on exposures and SLE severity (disease activity and damage)
- Examples of specific gene-environment interactions
- Environmental pollutants and SLE
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Cooper, G. (2007, October 1). Occupational and environmental influences on the development and course of lupus [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved January 10, 2025, from https://doi.org/10.69645/WFMR5521.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Glinda Cooper has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.
Occupational and environmental influences on the development and course of lupus
A selection of talks on Genetics & Epigenetics
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