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1. Introduction
2. Overview
3. Autoimmune diseases (1)
4. Autoimmune diseases (2)
5. Genes and autoimmune disease (1)
6. Genes and autoimmune disease (2)
7. Genes and autoimmune disease (3)
8. What do we know about Lupus?
9. Incidence of SLE among woman by age (1)
10. Incidence of SLE among woman by age (2)
11. Pathogenesis of Lupus
12. Causes of Lupus (1)
13. Causes of Lupus (2)
14. Number of Lupus publications by year and type
15. Environment and Lupus
16. Environment influences on risk of developing Lupus
17. Occupational risk factors silica dust
18. Silica and Lupus: descriptive and cohort studies
19. Silica dust and Lupus: case control studies
20. Silica dust and Lupus: clinical issues
21. Silica dust and Lupus: experimental studies
22. Silica dust and Lupus: other mechanistic issues
23. Solvents
24. Solvents and Lupus
25. Smoking and hair dyes - rationale
26. Smoking and Lupus
27. Hair dyes and Lupus
28. Potential gene-environment interactions
29. Suggestive gene-environment interactions
30. What is ultraviolet radiation?
31. Sun exposure and Lupus
32. Sun exposure and Lupus: case control studies
33. Environmental influences on severity of Lupus
34. Measures of disease severity or progression
35. Disease activity and disease damage
36. What about smoking?
37. Hair dyes and disease severity
38. Environmental pollutants and Lupus
39. Environmental pollutants: air
40. Environmental pollutants: air and water
41. Environmental pollutants: food
42. Mercury exposure and Lupus
43. Conclusions: studying "environment" is worthwhile
44. Conclusions: gene-environment interactions
45. Conclusions: interdisciplinary exchange
46. Understanding the etiology of Lupus
47. References (1)
48. References (2)
49. References (3)
50. References (4)
51. References (5)
52. References (6)
53. References (7)
54. References (8)

Topics Covered

• Role of genetic susceptibility in the etiology of systemic lupus erythematosus (SLE)
• Demographic risk factors for SLE
• Epidemiologic and experimental research on occupational exposures (respirable silica dust and solvents) and risk of developing SLE
• "Lifestyle" factors (smoking, use of hair dyes) and risk of developing SLE
• Ultraviolet radiation and risk of developing SLE
• Research on exposures and SLE severity (disease activity and damage)
• Examples of specific gene-environment interactions
• Environmental pollutants and SLE

Links

Series:

• Gene-Environment Interactions

Categories:

• Genetics & Epigenetics

Therapeutic Areas:

• Immunology & Inflammation

Talk Citation

Cooper, G. (2007, October 1). Occupational and environmental influences on the development and course of lupus [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 18, 2025, from https://doi.org/10.69645/WFMR5521.
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Publication History

• Published on October 1, 2007
• Archived on September 17, 2015

Financial Disclosures

• Dr. Glinda Cooper has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.