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1. Introduction
2. Why are bacterial plasmids important?
3. Plasmids - selective forces and beneficial traits
4. Transfer systems evolve faster on plasmids
5. Plasmids and gene exchange
6. Transfer apparatuses promote biofilm formation
7. Recombination processes and plasmid diversity
8. Evidence of past integration events
9. Lessons from bacterial genetics
10. Annual succession in a microcosm
11. Habitats of Pseudomonas species
12. Pseudomonas plasmids
13. Diverse plasmid families - incompatibility groups
14. An Incp-9 plasmid - pWWO
15. An IncP-6 plasmid - Rms149
16. Plasmid backbones
17. Acquisition and clustering of plasmid functions
18. Deletions and insertions during clustering
19. Examples of clusters of basic functions
20. IncP-9-alpha basic replicon organisation
21. Regulatory integration and interdependence
22. IncP-1 plasmids - RK2 is the archetype
23. Properties of IncP-1 plasmids
24. Global regulatory circuits on RK2
25. Definition of cooperativity
26. KorB can interact cooperatively with TrbA/KorA
27. Role of "orphan" KorB sites in plasmid partitioning
28. Role of "orphan" KorB sites in regulatory circuits
29. Purpose of the regulatory circuits
30. Conclusions

Topics Covered

• Why are plasmids important?
• Plasmids and gene exchange
• Pseudomonas plasmids illustrate diversity through modular structures
• Plasmid backbones and their building blocks
• IncP-1 plasmids as an example of sophisticated circuitry to extend host range and minimize burden on host

Links

Series:

• Biology and Significance of Plasmids

Categories:

• Microbiology

Therapeutic Areas:

• Infectious Diseases

Talk Citation

Thomas, C. (2008, January 28). Evolution of plasmids and their role in bacterial diversity and adaptability [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 3, 2024, from https://doi.org/10.69645/VJGA2713.
Export Citation (RIS)

Publication History

• Published on January 28, 2008

Financial Disclosures

• Prof. Christopher Thomas has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.