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Cutaneous T-cell lymphomas

Published on September 30, 2024   40 min

A selection of talks on Cancer

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0:00
It is my pleasure to give a lecture on cutaneous T-cell lymphomas. My name is Werner Kempf. I'm the co-director of Kempf and Pfaltz Histologische Diagnostik, a pathology laboratory here in Zurich, Switzerland, and professor at the Department of Dermatology at the University of Zurich.
0:34
Lymphocytes are the cells in the immune system which are present in the blood as part of the compartment of white blood cells in organs of the lymphatic system, particularly in the lymph nodes, as well as in other organs. For example, the skin. There are three main types of lymphocytes: B cells, T cells, and natural killer cells.
1:01
Lymphomas are neoplastic proliferations of lymphocytes. They may either originate in lymph nodes and called nodal lymphomas, or in other body sites and called extranodal lymphomas. Actually, lymphomas are one of the most common form of cancer, so two major groups of lymphomas are distinguished, Hodgkin lymphoma and non-Hodgkin lymphomas. In the lymph nodes, most lymphomas originate from B cells, whereas in the skin, most lymphomas originate from T cells. Lymphomas span a broad spectrum of neoplasias, which differ in regard to their clinical manifestation, their histological features, genetic changes, as well as the prognosis.

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