Printable Handouts

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Navigable Slide Index

1. Introduction
2. Outline
3. Components of energy metabolism
4. Aerobic fuels
5. Substrate oxidation
6. Metabolically active tissues
7. Energy balance
8. Substrate balance
9. Impact of substrate balance on energy intake
10. Partitioning of energy expenditure
11. Basal energy expenditure
12. Thermogenesis
13. Thermogenic response to meal
14. Thermogenic response to adrenaline
15. Activity energy expenditure
16. Non-exercise activity thermogenesis
17. Body composition and basal metabolism
18. Resting EE per organ for non-obese adults
19. Adipose tissues
20. White adipose tissue function
21. TAG storage and release
22. Lipid metabolism
23. Adipokines and other adipocyte products
24. Leptin
25. Leptin and regulation of body weight / fat content
26. Other factors affecting plasma leptin
27. Adiponectin
28. Inflammatory cytokines
29. Plasma cytokines after weight loss
30. Inflammatory cytokines in morbid obesity
31. Visceral vs. sub-cutaneous adipose tissue
32. Improved insulin sensitivity after weight loss
33. Brown adipose tissue
34. Skeletal muscle criteria
35. Skeletal muscle fibre types
36. Skeletal muscle fibre types in obesity
37. Metabolic disturbances in obesity
38. Skeletal muscle and weight loss
39. TAG, gene expression and insulin resistance
40. RMR in obesity (general)
41. RMR in an obese person
42. Dietary thermogenesis in obesity
43. Effect of meal pattern on metabolic responses (1)
44. Effect of meal pattern on metabolic responses (2)
45. Physical activity in obesity
46. Low exercise capacity in the obese
47. Conclusions

Topics Covered

• Components of energy metabolism
• Aerobic fuels
• Energy and substrate balance
• Partitioning of energy expenditure
• Adipose tissue
• Skeletal muscle
• Metabolic disturbances in obesity

Links

Series:

• Obesity

Categories:

• Clinical Practice
• Metabolism & Nutrition

Therapeutic Areas:

• Cardiovascular & Metabolic

Talk Citation

Macdonald, I. (2007, October 1). Metabolic, adipose tissue and muscle predictors of obesity [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved April 19, 2025, from https://doi.org/10.69645/YKAC7894.
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Publication History

• Published on October 1, 2007

Financial Disclosures

• Prof. Ian Macdonald has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.