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0:00
Hello. My name is Kevin Yuen.
I'm the Professor of
Medicine and Medical
Director of the Barrow
Neurological Institute,
Pituitary Center in
Phoenix, Arizona.
Today my talk to you is titled,
Adult Growth Hormone
Deficiency: Current
Understanding Diagnosis
and Treatment.
0:20
These are my disclosures.
0:24
So for my talk today,
I would like to start off with
a case example of a patient that
presented to me recently with
adult onset growth
hormone deficiency.
He's a 54 year old male with
Non-Functioning Pituitary
Adenoma, underwent pituitary
surgery four years ago,
and stereotactic radiosurgery
three years ago.
Now he has underlying TSH
and ACTH deficiencies,
for which he is on stable doses
of levothyroxine
and hydrocortisone.
At his most recent clinic
follow up appointment,
he had a blood test where
his IGF one standard
deviation score was -1.7.
His main complaint now is that
he's noticing some
weight gain of
ten pounds over the
past six months
and increased fatigue.
He does have a family history of
osteoporosis,
hyperlipidemia and cancer.
He has read up on the Internet
about the condition called
adult growth hormone
deficiency and would
like to be considered
for treatment for this.
1:23
For this patient, what
are the discussion points
that one needs to be considering
when seeing this patient?
On this slide here
you can see that
the condition adult growth
hormone deficiency and why
treat it certainly
something that needs to be
addressed then followed
by who to screen,
how to screen, and
once the patient has
confirmed adult growth
hormone deficiency,
how to start growth
hormone therapy,
and how to monitor
treatment efficacy.
There's also the issue of
discussing with
the patient about
potential safety concerns with
long term growth
hormone replacement
and also potential use or
misuse of growth
hormone replacement
for anti aging purposes.