Pancreatogenic diabetes: what is it and what to do about it?

Published on March 30, 2023   28 min

A selection of talks on Immunology & Inflammation

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0:00
Hello, I'm Phil Hart, Professor of Medicine at the Ohio State University. Today we'll be discussing pancreatogenic diabetes, including what is it, what to do about it?
0:12
Here are my potentially relevant financial disclosures.
0:17
In this session we'll be covering pancreatogenic diabetes from a number of facets including discussing what is it? Why does it matter? How do we diagnose it? How should we treat it? Then we'll move on to discuss what have we learned recently regarding this condition, and what are the next steps forward?
0:35
To begin, we'll try to define what is it.
0:40
Pancreatogenic diabetes refers to diabetes that occurs secondary to any disease of the exocrine pancreas. This can include acute or chronic pancreatitis, cystic fibrosis, hemochromatosis, pancreatic cancer, or following pancreatic surgery, either a partial pancreatectomy or total pancreatectomy. It's important to understand that pancreatogenic diabetes is an umbrella term that really describes a collection of different entities. As a consequence of this, it represents a heterogeneous mix of conditions, each of which, we believe, have unique aspects of pathophysiology, and as a result of this, potential considerations as it relates to treatment.
1:25
There are a number of synonyms that are currently used to describe pancreatogenic diabetes. The most common alternative term is type 3c diabetes, which we'll touch on more in a moment here. You can see there's a list of four or five other synonyms for this group of disorders. As Shakespeare described in Romeo and Juliet, what something is called or labeled is often arbitrary and less important compared to its underlying intrinsic qualities, which we'll describe in more detail.

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