Crampology: pathophysiology and diagnosis of muscle cramps

Published on February 28, 2023   18 min

A selection of talks on Cardiovascular & Metabolic

Please wait while the transcript is being prepared...
0:00
Hello, my name is Dr. Hans Katzberg, I'm a neurologist and Associate Professor of Medicine at the University of Toronto. I work at the Prosserman Centre for Neuromuscular Diseases, and I'm going to be speaking about muscle cramps today. I'd like to title this first talk, Crampology 101, where I will focus on the pathophysiology and diagnosis of muscle cramps. We'll focus on treatment in the next set of slides.
0:28
The objectives today are to define firstly, muscle cramps; in particular, we'll be focusing on neurogenic muscle cramps as these are more common in contrast to a myopathic muscle cramp, which has a different electrical signature and different and distinct kind of pattern. I would like to also talk a little bit about other hyper-excitable neurological phenomena. This is relevant to not only clinicians but also to electrophysiologists who are able to identify electrical activity from muscles when they do electromyography. Then, I'll talk a little bit about the pathophysiology that leads to these muscle cramps and particularly focusing on electrophysiological features.
1:08
I'll start with a clinical case. This is a 46-year-old man who was previously healthy and complains of tightness in his legs for the last year. These episodes occur and are defined as episodes. However, it can occur at any time without a trigger frequently at the end of exercise. The questions through this clinical case are, what is the definition of a muscle cramp and what is the differential diagnosis in regards to phenomenology and how does one distinguish these different entities? In regards to this case, it is somewhat vague on purpose because these are the difficulties that one gets. One encounters patients who may not know what you mean when you were talking about muscle cramps and they may sometimes define things as tightness, which is rather non-specific. One feature, as I've mentioned, is that the patient is describing these as episodes. I think helps to distinguish cramps which do occur in very distinct episodes from other more nonspecific and extended phenomena, or discomfort or pain, which can happen. The fact that these happened frequently at the end of exercising, maybe your clue as well, that these own fact neurogenic muscle cramps as dehydration can lead to these phenomena.
Hide

Crampology: pathophysiology and diagnosis of muscle cramps

Embed in course/own notes