• Introduction to the World of Hormones
• 45 min
  1. Introduction to hormones

  • Prof. Helen Henry
• The Reproductive Hormones
• 44 min
  2. Endocrinology of parturition

  • Dr. Errol Norwitz
• 54 min
  3. Menopausal hormone therapy

  • Prof. Hugh Taylor
• 53 min
  4. Understanding hormones: mechanisms of androgen receptor function in reproduction and cancer

  • Prof. Elizabeth Wilson
• Hormones in Calcium and Phosphorus Homeostasis
• 36 min
  5. Vitamin D endocrine system: basics

  • Prof. Anthony Norman
• 47 min
  6. Vitamin D endocrine system: mechanisms to produce biological responses

  • Prof. Anthony Norman
• 37 min
  7. Parathyroid hormone and parathyroid hormone-related protein

  • Prof. Robert Nissenson
• 51 min
  8. Hormonal influence on bone remodeling and its implications for the pathophysiology of osteoporosis

  • Prof. Stavros Manolagas
• Hormones and the Vasculature
• 52 min
  9. Vascular cell signaling by membrane estrogen receptors

  • Prof. Jeffrey Bender
• Hormones and Energy Metabolism
• 41 min
  10. Pathogenesis of the metabolic syndrome

  • Prof. Richard Bergman
• Hormones and Growth
• 31 min
  11. The growth hormone/insulin-like growth factor-1 axis in health and disease

  • Prof. Derek LeRoith
• Frontiers in Hormone Research
• 47 min
  12. Prevention of type 1 diabetes

  • Prof. Chantal Mathieu
• 27 min
  13. Actions of steroid hormones in the brain

  • Prof. Bruce McEwen
• 40 min
  14. Vitamin D and prostate cancer

  • Prof. David Feldman
• Archived Lectures *These may not cover the latest advances in the field
• 46 min
  15. G-protein coupled receptors: hormone membrane receptors

  • Prof. Stuart Sealfon
• 40 min
  16. Nuclear receptors: transcriptional functions

  • Prof. Nancy Weigel
  • Dr. Neil McKenna
• 60 min
  17. Steroid hormones and their receptors in breast cancer

  • Prof. JoEllen Welsh
• 44 min
  18. Nuclear receptor superfamily: structural insights into function

  • Prof. Dino Moras
• 53 min
  19. Receptor tyrosine kinases - function, families and evolution

  • Prof. Tony Hunter
• 58 min
  20. Can we prevent type I diabetes?

  • Prof. Chantal Mathieu
• 39 min
  21. Vitamin D endocrine system: VDR binding, nutrition and drugs development

  • Prof. Anthony Norman

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Hormones and breast cancer
3. Cellular origin of breast cancer
4. Stages in cancer development
5. Different types/stages of breast cancers
6. Established hormonal risk and protective factors
7. Hormones and the etiology of breast cancer
8. Steroid hormone receptor isoforms
9. Steroid hormone mechanism of action
10. Structural basis of DNA binding
11. Additional estrogen/estrogen receptor pathways
12. ER effectors
13. ER-alpha and estrogen in breast tumors
14. Hormonal issues in breast cancer treatment
15. Hormone replacement therapy
16. Women's health initiative study
17. Environmental "estrogens"
18. Estrogen synthesis and metabolism
19. Synthetic ER ligands and cellular responses
20. Tamoxifen therapy for breast cancer
21. Prevention of breast cancer?
22. Alternative hormonal approaches
23. Additional hormones affecting breast cancer
24. Summary and outstanding research questions

Topics Covered

• Development and types of breast cancers
• Molecular and cellular aspects of hormone action on breast cells
• Natural and synthetic estrogens
• Basis for endocrine therapies
• Alternative/emerging therapeutic approaches
• Strategies for breast cancer prevention

Links

Series:

• The World of Hormones

Categories:

• Biochemistry
• Cancer
• Reproduction & Development

Therapeutic Areas:

• Oncology

Talk Citation

Publication History

• Published on December 1, 2007
• Archived on August 13, 2020

Financial Disclosures

• Prof. JoEllen Welsh has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.