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Navigable Slide Index

1. Introduction
2. Inheritance of different segments of the genome
3. Types of human genomic studies: biomedical
4. Types of human genomic studies: anthropological
5. Types of human genomic studies: clinical
6. Collection of samples
7. What is sampling?
8. Questions to consider when sampling
9. Defining the study population (1)
10. Defining the study population (2)
11. Representativeness
12. Sampling methods
13. Sampling strategies for qualitative studies
14. Test hypothesis and random sampling (probability)
15. Study population units has to be equal
16. Random strategies to collect quantitative data
17. Simple random sampling
18. Systematic sampling
19. Stratified sampling
20. Cluster sampling
21. Multi-stage sampling
22. Bias in sampling
23. Ethics and genetic research
24. Human subjects benefits and informed consent
25. Informed consent
26. Confidentiality
27. Benefits and Harm
28. Examples of genetic research ethics guidelines (1)
29. Examples of genetic research ethics guidelines (2)
30. Human origins
31. Why Africa?
32. Linguistic groupsin sub-Saharan Africa
33. Reconstructing human migration patterns
34. Challenges in field work
35. The importance of dialog with people in field work
36. Ethical questions from the community
37. Sampling in the field
38. The Lemba people and their genetic background
39. Strategy for sampling within sub-Saharan Africa
40. Map patterns of genetic variation within Africa
41. Examine genetic affinities of living peoples
42. Write the history of the peoples of Africa

Topics Covered

• Use of genomic DNA to advance our knowledge and understanding of human evolution, biomedical research and mechanisms of disease
• Acquiring specimens for research
• Strict policies and recommendations guiding specimen acquirement
• Social, ethical and legal issues when conducting research on human subjects
• Factors to be considered when setting up qualitative and quantitative research
• Case study: sub-Saharan Africa, in particular population genetics studies

Links

Series:

• Using Bioinformatics in the Exploration of Genetic Diversity

Categories:

• Genetics & Epigenetics
• Methods

Talk Citation

Soodyall, H. (2007, October 1). Population genetics studies in Africa: curiosity and challenges [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 26, 2024, from https://doi.org/10.69645/SFRR2247.
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Publication History

• Published on October 1, 2007
• Archived on October 28, 2018

Financial Disclosures

• Prof. Himla Soodyall has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.