Topics Covered
- Potential metabolic fates of pyruvate
- Lactate transport
- Role of pyruvate dehydrogenase complex (PDC)
- Regulation of PDC
- Mechanisms of activation of PDC by pyruvate dehydrogenase phosphatases
- Pyruvate dehydrogenase kinase (PDK) expression and regulation
- Multi-site phosphorylation
- Transcription factors regulating PDK4 expression
- Anaplerosis and cataplerosis
- Pyruvate carboxylase
- Insulin secretion and action
- Glucose/fatty-acid cycle
- Consequences of PDK4 upregulation
- Disorders of pyruvate handling
Links
Series:
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Talk Citation
Sugden, M. (2007, October 1). Modifications of pyruvate handling in health and disease [Video file]. In
The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 1, 2023, from
https://hstalks.com/bs/45/.
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Publication History
-
Published on October 1, 2007
Financial Disclosures
- Prof. Mary Sugden has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.