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- Biochemistry
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1. De novo designed proteins: a breakthrough in snakebite treatment
- Dr. Susana Vazquez Torres
- Cancer/Oncology
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3. From lab to clinic: bridging cancer genetics and public health
- Prof. Clare Turnbull
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4. Engineered yeast: a breakthrough in targeted cancer therapies
- Prof. Gautam Dantas
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6. Cancer vaccines
- Dr. Elias Sayour
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7. The future of blood tests in cancer treatment
- Dr. Isaac Garcia-Murillas
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9. Artificial intelligence in precision medicine
- Dr. Michael P. Menden
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10. How liver X receptor regulates intestinal regeneration and tumor growth
- Dr. Srustidhar Das
- Immunology & Inflammation
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11. Role of ETS2 in autoimmune and inflammatory diseases
- Dr. James Lee
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12. Rheumatic diseases and musculoskeletal pain
- Prof. Anisur Rahman
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14. Transmembrane domains and the regulation of trogocytosis in T cells
- Dr. Stefano Barbera
- Infectious Diseases/Microbiology
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16. Kalihinol analog MED6-189: a promising pan-antimalarial candidate
- Prof. Karine Le Roch
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17. Elite controllers of HIV: from discovery to future therapies
- Prof. Bruce Walker
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19. Towards developing a universal influenza vaccine
- Prof. Peter Palese
- Methods
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21. How big data and genomics are personalizing your health- Prof. Michael Snyder
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22. The role of preregistration and registered reports in improving research transparency and reproducibility
- Dr. Peter Bonde Ernst-Rasmussen
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23. Decoding aging: how a proteomic clock predicts mortality and disease across populations
- Dr. M. Austin Argentieri
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24. MassBank development and future
- Dr. Emma L. Schymanski
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25. Synthetic whole embryo models and their applications
- Prof. Jacob (Yaqub) Hanna
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26. Pioneering proteomics: insights on advancements in the science of proteins
- Prof. Ruedi Aebersold
- Neurology/Neuroscience
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27. Duchenne muscular dystrophy: pathology, diagnostic strategies, and core molecular pathways- Prof. Steve Wilton
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28. Rethinking the amyloid dogma in Alzheimer’s disease
- Prof. George Perry
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29. Integrated multimodal cell atlas of Alzheimer’s disease
- Dr. Michael Hawrylycz
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30. How and why neurons die in Alzheimer's disease?
- Prof. Bart De Strooper
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31. Restoring glucose metabolism: a new approach to reversing cognitive decline in AD
- Prof. Katrin Andreasson
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32. Advancing ALS genetics through accessible testing
- Dr. Teresa Fecteau
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33. MicroRNA as a biomarker for early detection of amyotrophic lateral sclerosis
- Dr. Sandra Banack
- Dr. Paul Alan Cox
- Dr. Rachael Dunlop
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34. Translational research in amyotrophic lateral sclerosis (ALS)
- Prof. Aaron D. Gitler
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35. Muscarinic acetylcholine receptor modulation in neurological diseases
- Prof. Andrew B. Tobin
- Pharmaceutical Sciences
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36. The state of the art in secondary pharmacology
- Dr. Jean-Pierre Valentin
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37. The safety, toxicology, and regulation of antibody-drug conjugates
- Dr. Veysel Kayser
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39. Management of generic drug development: challenges and opportunities
- Mr. Sandeep Patil
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40. Translational medicine: the risk of failure in delay and how to reduce it
- Prof. Martin Wehling
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41. Artificial intelligence in guiding cancer treatment decisions
- Prof. Eytan Ruppin
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42. The regulation of cell therapy
- Prof. Moutih Rafei
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43. Scale-up challenges in the production of nanomedicines from lab to industry
- Prof. Dr. Oya Tagit
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44. Challenges and solutions of scaling up
- Dr. Shaukat Ali
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46. Using real-world insights on drug interactions to inform drug development
- Dr. Amita Datta-Mannan
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47. Role of marketing authorization holder in drug safety
- Dr. Raphael Elmadjian Pareschi
Topics Covered
- The discovery of HIV and elite controllers
- Initial research and clinical trials
- From HIV elite controllers to an HIV vaccine
- HIV structural constraints, structurally important regions and viral fitness
- Current and future challenges in HIV treatments
Biography
Bruce D. Walker, M.D. is the Phillip T. and Susan M. Ragon Professor of Immunology and Medicine at Harvard Medical School, Professor of Microbiology and Immunobiology at Harvard T.H. Chan School of Public Health, and a Howard Hughes Medical Institute (HHMI) Investigator. He is the founding and current director of the Ragon Institute of MGH, MIT and Harvard, whose mission is to create cross-disciplinary collaborations in order to harness the immune system to prevent and cure human disease. In addition to his clinical duties as an Infectious Disease specialist at Massachusetts General Hospital, his research focuses on cellular immune responses in chronic human viral infections, with a particular focus on HIV immunology and vaccine development. He leads an international translational clinical and basic science research effort to understand how some rare people who are infected with HIV, but have never been treated, can fight the virus with their immune system.
Dr. Walker is also an Adjunct Professor at the Nelson Mandela School of Medicine in Durban, South Africa. He is a co-founder of the KwaZulu-Natal Research Institute for TB and HIV (K-RITH, recently renamed the Africa Health Research Institute, AHRI), an initiative initially funded by HHMI to build a state-of-the-art TB/HIV research facility at the heart of these dual epidemics in South Africa.
Dr. Walker is also a member of the American Academy of Arts and Sciences, American Society for Clinical Investigation (ASCI), the American Association of Physicians (AAP), and the National Academy of Medicine. He received his M.D. from Case Western Reserve University and his B.A. in Chemistry from the University of Colorado, and has been on the Harvard faculty since 1980.
Links
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Talk Citation
Walker, B. (2020, April 14). Elite controllers of HIV: from discovery to future therapies [Audio file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved June 17, 2026, from https://doi.org/10.69645/MXJT2430.Export Citation (RIS)
Publication History
- Published on April 14, 2020
Financial Disclosures
- There are no commercial/financial matters to disclose