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1. Introduction
2. Essential antioxidants
3. Daily intake of essential antioxidants
4. Polyphenols have antioxidant properties
5. Free radicals and immune cell function
6. Animals' response to different pathogens
7. Antioxidant defenses in immune infection
8. Inflammatory periodontitis and serum antioxidants
9. Vitamin E content of blood composition
10. Antioxidants-host defense-infection interaction (1)
11. Vitamin E deficiency and the immune responses
12. Vitamin E deficiency and human immune response
13. Numerous CVB3 variants exist
14. Experiment by Beck et al.
15. Beck's study design
16. Nucleotide and amino acid changes
17. Beck's experiment's findings
18. Antioxidants-host defense-infection interaction (2)
19. Infectious diseases in the elderly
20. Effect of host age on CVB3 virulence
21. T cell mediated immune function
22. Effect of host on CVB3 virulence
23. Virus origin effect on recipient young mice survival
24. Virus origin effect on young mice heart pathology
25. Effect of passage through an old vs. young host
26. Antioxidant supplementation (1)
27. Vitamin E and immune response in the aged
28. Blood vitamin E levels and change in DTH
29. Antioxidant supplementation (2)
30. Vitamin E decreases mice lung influenza viral titer
31. Effect of micronutrient supplement on DTH
32. Antioxidant supplementation (3)
33. Resveratrol and curcumin effect on T cells
34. Clinical benefit from antioxidant supplementation?
35. Experimental design
36. Primary outcomes in the study
37. Secondary outcomes in the study
38. Study profile
39. Vitamin E supplementation and plasma vitamin E
40. Effect of vitamin E on respiratory infections
41. Effect of vitamin E on common colds
42. Vitamin E status and pneumonia
43. Study conclusion
44. Study implications
45. Serum Zn levels and pneumonia in elderly
46. Effect of zinc supplementation on infection
47. Zn supplementation and oxidative stress markers
48. Effect of Se supplementation on poliovirus
49. Selenium and immune response and infection
50. Serum Se in healthy subjects and HIV patients
51. How do antioxidants exert their effect?
52. Vitamin E-induced T cell function enhancement
53. Age and vitamin E effects on naive T cells
54. Effect of vitamin E on gene expression
55. T cell activation
56. Hypothesis
57. Experiment 1: in vitro study design
58. Detecting effective immune synapses formation
59. Vitamin E effect on immune synapse formation (1)
60. Vitamin E effect on immune synapse formation (2)
61. Summary
62. Antioxidants and immune response
63. Acknowledgements (1)
64. Acknowledgements (2)
65. Acknowledgements (3)

Topics Covered

• Essential antioxidants
• Antioxidant defenses in immune infection
• Antioxidants-host defense-infection: a complex interaction
• Vitamin E deficiency
• CVB3
• Effect of host age
• Effect of virus origin
• Effect of passage
• Antioxidant supplementation
• Vitamin E and immune response in the aged
• Not all antioxidants behave the same
• Clinical benefits from antioxidant supplementation
• Zinc supplementation
• Selenium
• How do antioxidants exert their effect?
• T-cell function

Links

Series:

• Free Radicals and the Oxygen Paradox

Categories:

• Biochemistry
• Immunology
• Microbiology

Therapeutic Areas:

• Immunology & Inflammation
• Infectious Diseases

Talk Citation

Meydani, S. (2007, November 1). Antioxidants and immune response and infectious diseases [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 23, 2024, from https://doi.org/10.69645/VVTV5430.
Export Citation (RIS)

Publication History

• Published on November 1, 2007
• Archived on May 31, 2018

Financial Disclosures

• Prof. Simin Meydani has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.