Today, I wish to present a lecture about "Developmental Genetics of Endometriosis".
In the present lecture, I wish to call your attention to our new hypothesis of endometriosis,
which we call "developmental genomics of endometriosis".
The title of my lecture is proved by a well-known fact
that almost 100 years past since endometriosis,
as a chronic disease,
was first described by Karl Rokitiansky in
1860 as a chronic estrogen-dependent inflammatory heritable disease,
affecting and debilitating approximately five to
10 percent of all women in their early reproductive age.
The problem of endometriosis remains in the focus of
intensive clinical and medical inspection as scientifical studies.
In spite of enormous effort,
a lot of information on numerous genetic, epigenetic,
endocrine, immunological studies, the pathogenesis of
endometriosis still remains enigmatical.
In our famous Ott's Institute of Obstetrics,
Gynecology and Reproductology in Saint-Petersburg,
Russia, the problem of endometriosis is in the focus of
clinical laboratory and theoretical studies for over 30 years.