Transport and delivery of neurotrophic peptides and proteins across the BBB

Published on January 31, 2017   34 min

Other Talks in the Series: The Blood-Brain Barrier

0:00
Hello, I am Dr. Weihong Pan. In this slide set, I will discuss "Transport and Delivery of Neurotrophic Peptides and Proteins across the BBB".
0:12
Here is the outline. The first part is about the blood-brain barrier, or BBB in short, to peptides and proteins with a discussion of flow-independent influx transport systems. The second part addresses influx transport of neurotrophic peptides and proteins. The third part will move to the biotechnology sector and the goals of CNS drug delivery. The last part will focus on physiological regulations, particularly those related to sleep and the circadian rhythms.
0:47
In part one, I will have a brief review of pertinent features of the BBB, discuss the dynamic context involving interstitial space, cerebrospinal fluid or CSF, and the cellular compartments. I will then summarize study methods including the classics and updates.
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Transport and delivery of neurotrophic peptides and proteins across the BBB

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