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Navigable Slide Index

1. Introduction
2. Outline
3. Depression
4. Modelling aspects of depression
5. Face, construct and predictive validity
6. Other types of validity
7. Testing for depressive-like behaviours
8. Tests for behavioural despair
9. Tests for anhedonia - sucrose preference test
10. Tests for anhedonia - female urine sniff test
11. Tests for anxiety behaviour
12. Tests for anxiety and apathetic behaviour
13. Tests for social behaviour
14. Overview of methodological approaches
15. Psychosocial stress
16. Social defeat stress
17. Other forms of psychosocial stress
18. Witnessing psychosocial stress
19. Neurobiological mechanisms - genetics
20. DCC
21. DCC and mIR-218
22. DCC and mIR-218 in mouse models
23. DCC knock-down models
24. Sex as a biological variable
25. Future directions
26. Acknowledgments
27. References

Topics Covered

• Depression
• Animal models
• Genetics
• Neurobiological mechanisms
• Psychosocial stress
• Types of validity

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Categories:

• Diseases, Disorders & Treatments
• Methods

Therapeutic Areas:

• Neurology

Talk Citation

Publication History

• Published on November 30, 2020

Financial Disclosures

• Dr. Anand Gururajan has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.