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1. Introduction
2. Questions about human population structure
3. Human genome diversity cell line panel
4. References
5. Microsatellites
6. Number of distinct alleles per locus
7. Genetic variation across populations: pie charts
8. Question 1: distribution of alleles
9. Geographic distribution of alleles: binary table
10. Geographic distribution of alleles: pie chart
11. Question 2: existence of distinctive alleles
12. Number of regionally private alleles per locus
13. Strongly diverged alleles
14. An allele private to the Americas
15. Question 3: genetic similarity among populations
16. Genome-wide pairwise differences
17. Partition of genetic variance
18. Question 4: determining geographic ancestry
19. Inference of ancestry using alleles' frequencies
20. Inferred population structure
21. Inferred population structure viewed on a map
22. Influence of the number of loci
23. Influence of the numbers of loci and individuals
24. Population structure for the X chromosome
25. Influence of the type of marker: indels
26. Inference of population ancestry
27. Question 5: origin of variation across populations
28. Heterozygosity and geography: simulations
29. Heterozygosity and geographic distance
30. The source of the human expansion
31. Serial sampling model
32. Serial sampling: locus TGA012
33. Clines or clusters?
34. Genetic and geographic distance in Asia
35. Genetic and geographic distance worldwide
36. Summary

Topics Covered

• Geographic distribution of genetic variants
• Private alleles
• Pairwise differences between individuals
• Partition of genetic variation
• Population structure and inference of ancestry
• Decline of heterozygosity with distance from Africa
• Serial sampling model for human evolution
• Clines and clusters

Links

Series:

• Human Population Genetics I

Categories:

• Genetics & Epigenetics

Talk Citation

Publication History

• Published on October 1, 2007

Financial Disclosures

• Prof. Noah Rosenberg has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.