• The Human Genome Project
• 28 min
  1. Major gene families in humans and their evolutionary history

  • Prof. Yoshihito Niimura
• 41 min
  2. Evolution of human mitochondrial DNA variations

  • Prof. Toomas Kivisild
• 51 min
  3. Ethical issues in human population genetics

  • Prof. Henry Greely
• Important Phenotypic Phenomena
• 56 min
  4. Genetics of breast and ovarian cancer

  • Prof. Jeffrey Weitzel
• 53 min
  5. Colorectal cancer and the rare variant hypothesis

  • Prof. Sir Walter Bodmer
• Archived Lectures *These may not cover the latest advances in the field
• 32 min
  6. The genetics of breast and ovarian cancer

  • Dr. Piri Welcsh
• 37 min
  7. Historical and geographical genetic variation: Europe

  • Prof. Antonio Torroni
• 40 min
  8. Linguistic evolution

  • Dr. Merritt Ruhlen
• 37 min
  9. Human microsatellite and minisatellite DNA polymorphisms

  • Dr. James Weber
• 41 min
  10. Human population genetics: lifespan

  • Prof. Kaare Christensen
• 33 min
  11. Major gene families in humans and their evolutionary history

  • Prof. Yoshihito Niimura
  • Prof. Masatoshi Nei
• 34 min
  12. Natural selection and sequence polymorphism

  • Prof. Austin Hughes
• 32 min
  13. Human Y chromosome phylogenetics and phylogeography

  • Prof. Peter Underhill
• 63 min
  14. The peopling of the Americas: new insights from genetic studies

  • Dr. Theodore Schurr
• 48 min
  15. History and geography of human genetic diversity I

  • Prof. Luigi Luca Cavalli-Sforza
• 40 min
  16. History and geography of human genetic diversity II

  • Prof. Luigi Luca Cavalli-Sforza
• 24 min
  17. History and geography of human genetic diversity III

  • Prof. Luigi Luca Cavalli-Sforza
• 46 min
  18. The HapMap project

  • Prof. Andrew Clark
• 37 min
  19. Genetic diseases in the Jewish population

  • Prof. Neil Risch
• 48 min
  20. The genetics of French Canadians

  • Dr. Bernard Brais
  • Dr. Bertrand Desjardins
  • Prof. Damian Labuda
  • Dr. Marc St-Hilaire
  • Prof. Marc Tremblay
  • Prof. Helene Vezina
• 33 min
  21. Human genetic variation of Africa

  • Prof. Joanna Mountain
• 66 min
  22. Evolution: how genes and their variation got here

  • Prof. Kenneth Weiss
• 20 min
  23. Modern human origins

  • Prof. Richard Klein
• 64 min
  24. The human genomes

  • Prof. Gil McVean
• 49 min
  25. The signature of local adaptations in human polymorphism data

  • Dr. Anna Di Rienzo
• 37 min
  26. Genetics of Pakistani populations in an Asian and global context

  • Prof. S. Qasim Mehdi
• 38 min
  27. Cultural evolution

  • Prof. Marcus Feldman
• 45 min
  28. The genetic component to diabetes

  • Dr. Nancy Cox
• 39 min
  29. Human population structure

  • Prof. Noah Rosenberg

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. The human genome diversity project (HGDP)
3. Political difficulties in 1993-4
4. The HGDP collection
5. Populations included in the HGDP
6. Paper obtained with the HGDP-CEPH collection
7. Estimated population structure
8. Explanation of the method structure
9. Basic clusters of the method structure
10. F. Blumenbach, the father of anthropology
11. Are partitions suggested by structure useful 'races'
12. Present limitations of HGDP-CEPH
13. Are structure established clusters 'good' races?
14. Races might be useful for medicine
15. Smaller races
16. Correlation of genetic and geographic distance
17. Two examples of the correlation
18. Drift and migration determine genetic variation
19. Drift and natural selection
20. Serial founder effect
21. Geographic distance vs. expected heterozygosity
22. Expansion from E. Africa - founder effects
23. Loss of heterozygosity due to founder effect
24. Coevolution of genes and languages
25. The world's language families
26. Families that survived with less important changes
27. Linguistic families
28. Genetic and linguistic trees
29. Darwin's statement
30. The complete tree of language evolution

Topics Covered

• The human genome diversity project (HGDP)
• Method structure
• Limitations of HGDP-CEPH
• Are the clusters established by structure "good" races?
• Correlation between genetic and geographic distance
• Decrease of genetic diversity in the human expansion as serial founder effect
• Coevolution of genes and languages
• Linguistic families: correlation of the genetic and linguistic trees
• Darwin's statement
• The complete tree of language evolution

Links

Series:

• Human Population Genetics I

Categories:

• Genetics & Epigenetics

Talk Citation

Publication History

• Published on October 1, 2007
• Archived on February 25, 2021

Financial Disclosures

• Prof. Luigi Luca Cavalli-Sforza has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.