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1. Introduction
2. COPD exacerbations
3. Airway bacteria - stable COPD & exacerbations (1)
4. RCT of antibiotic therapy
5. Sputum characteristics
6. Bacterial eradication & inflammation
7. Changes in bacterial load
8. Risk of exacerbation & bacterial strain change
9. Strain change & bacterial load relationship
10. Lung microbiome in smoker vs. COPD (1)
11. Lung microbiome in smoker vs. COPD (2)
12. Respiratory viruses & exacerbation
13. Exacerbation recovery after onset
14. HRV and COPD exacerbations
15. Effect of common colds on IL6 in induced sputum
16. Plasma fibrinogen at exacerbation
17. Exacerbation frequency & common cold in COPD
18. Susceptibility of COPD patients to rhinovirus
19. Eosinophilic markers of viral exacerbations
20. Lower airway bacteria & rhinoviral infection
21. Sputum IL1B at bacterial exacerbations
22. Change in IP10 from baseline to exacerbation
23. IP10 ROC curve analysis
24. Airway bacteria - stable COPD & exacerbations (2)
25. Bacterial load & airway inflammation
26. Airway bacterial load & FEV1 decline
27. Lower lobe bronchiectasis - COPD & inflammation
28. Doxycycline vs. placebo (1)
29. Doxycycline vs. placebo (2)
30. Exacerbation frequency & bacterial colonization
31. Long term antibiotics
32. Patients with purulent/mucopurulent sputum
33. Macrolides - time to 1st exacerbation
34. Macrolides - sputum markers
35. Macrolide (Azithromycin) study
36. Macrolide study - subgroup analysis
37. RSV infection in stable COPD
38. Patterns of RSV infection
39. RSV & FEV1 decline
40. High sputum myeloperoxidase in COPD with RSV
41. Conclusion

Topics Covered

• Roles of viral and bacterial infections at exacerbations of COPD
• Airway bacteria
• RCT of antibiotic therapy
• Sputum characteristics
• Bacterial eradication & inflammation
• Bacterial strain change
• Lung microbiome in smoker vs. COPD
• Plasma fibrinogen at exacerbation
• Exacerbation frequency & common cold in COPD
• Rhinovirus
• Eosinophilic markers of viral exacerbations
• Lower lobe bronchiectasis
• Doxycycline vs. placebo
• Long term antibiotics
• Patients with purulent/mucopurulent sputum – Macrolide studies
• RSV infection in COPD

Links

Series:

• Respiratory Infection

Categories:

• Clinical Practice
• Microbiology

Therapeutic Areas:

• Infectious Diseases
• Respiratory Diseases

Talk Citation

Publication History

• Published on July 11, 2013

Financial Disclosures

• Prof. Wisia Wedzicha has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.