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1. Introduction
2. Conflict statement
3. Outline
4. The SEARCH study
5. The latency period in the development of T1D
6. Time to diabetes by number of Abs
7. TrialNet and immune tolerance network
8. Trial Net intervention studies
9. Prevention and early diagnosis
10. The diagnosis of T1D in children and youth
11. Work up of diabetes type in youth
12. Catastrophe at diagnosis - DKA
13. The diagnosis
14. Diabetes is hard to manage
15. What is the course of type 1 diabetes
16. DCCT, EDIC and rate of severe hypoglycemia
17. The importance of glycemic control
18. The insulin pump: more like a healthy pancreas
19. Insulin pump therapy improves control
20. CSII reduces incidents of severe hypoglycemia
21. Continuous glucose monitoring
22. Early control and beta-cell preservation
23. STAR 3 study sites
24. Study population
25. A1C at 3, 6, 9, 12 months: all patients
26. A1C at 3, 6, 9, 12 months: adults >= 19 years
27. A1C at 3, 6, 9, 12 months: pediatrics 7–18 years
28. A1C reduction is correlated with sensor use
29. Cumulative severe hypoglycemia and DKA
30. The benefit of early control
31. Mean A1C values, SAP and crossover groups
32. Prevalence of CVD risk factors in youth
33. Helping the student with diabetes succeed
34. The role of healthcare provider in treatment
35. Evolution of a fully-automated delivery system
36. How does LGS work?
37. Low glucose suspend does what it is meant to do
38. Subset of data mining
39. Initial observations: children and adolescents
40. Alert and suspend settings, all ages vs. pediatric
41. Distribution of LGS events, all ages v pediatric (1)
42. Distribution of LGS events, all ages v pediatric (2)
43. LGS – glucose rate of change (ROC)
44. Conclusions about LGS first automated feature
45. Trial Net intervention studies (2)
46. The closed loop system
47. Overnight closed-loop glucose control
48. The closed-loop in pediatric subjects
49. Glucose values: home SCII vs. closed loop
50. Closed-loop Insulin delivery – RCT
51. Conclusions

Topics Covered

• The SEARCH study
• The latency period in the development of T1D
• Time to diabetes by number of Abs
• TrialNet and Immune Tolerance Network international consortia
• Prevention and early diagnosis
• The diagnosis of T1D in children and youth
• Work up of diabetes type in youth
• Catastrophe at diagnosis: DKA
• What is the course of type 1 diabetes
• DCCT, EDIC and rate of severe hypoglycemia
• The importance of glycemic control
• The insulin pump: more like a healthy pancreas
• CSII reduces incidents of severe hypoglycemia
• Continuous glucose monitoring
• Early control and beta-cell preservation
• STAR 3 study
• A1C reduction is correlated with sensor use
• Prevalence of CVD risk factors in youth
• The role of healthcare provider in treatment
• Evolution of a fully-automated delivery system
• How does LGS work?
• The closed-loop system

Links

Series:

• Diabetes in Perspective

Categories:

• Clinical Practice
• Metabolism & Nutrition

Therapeutic Areas:

• Cardiovascular & Metabolic

Talk Citation

Publication History

• Published on May 22, 2013

Financial Disclosures

• Prof. Francine Kaufman has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.