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- Epidemiology and Risk Factors
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1. The changing prevalence of asthma
- Dr. Deborah Jarvis
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2. Recent advances in asthma genetics
- Prof. Miriam Moffatt
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3. Asthma: an epidemic caused by epigenetics?
- Prof. David Schwartz
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4. Role of the microbiota in asthma
- Prof. B. Brett Finlay
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5. Diet and asthma
- Prof. Lewis Smith
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6. Obesity and asthma
- Prof. Anne Dixon
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7. Occupational asthma: management beyond the textbooks
- Prof. Paul Cullinan
- Clinical Phenotypes
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8. The origins of asthma
- Prof. Peter Sly
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9. Pre-school wheeze
- Prof. Andrew Bush
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11. Smoking asthmatics
- Prof. Neil Thomson
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12. Aspirin exacerbated respiratory disease
- Prof. Chris Corrigan
- Mechanisms of Asthma
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13. Advances in asthma: airway inflammation
- Prof. William Busse
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14. The role of mast cells in asthma
- Prof. Peter Bradding
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15. Dendritic cells in asthma
- Prof. Bart Lambrecht
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16. The airway smooth muscle in asthma
- Prof. Judith Black
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17. Role of virus infection in asthma 1
- Prof. Sebastian Johnston
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18. Role of virus infection in asthma 2
- Prof. Sebastian Johnston
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19. Severe asthma: characterisation, mechanisms & treatment
- Prof. Fan Chung
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20. Steroid resistance in asthma: mechanisms and potential therapies
- Prof. Ian Adcock
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21. Macrophage in asthma
- Prof. Douglas Robinson
- Diagnosis of Asthma
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22. Physiology of asthma and involvement of small airways
- Prof. Charles G. Irvin
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23. Induced sputum in asthma
- Prof. Antonio Spanevello
- Therapy and Management
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25. Pulmonary drug delivery
- Prof. Anthony J. Hickey
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26. The management of chronic asthma
- Prof. Mark Fitzgerald
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27. Inhaled corticosteroids and beta2-agonists
- Dr. Omar S. Usmani
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28. Management of "difficult asthma"
- Prof. Elisabeth Bel
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29. Management of acute exacerbations of asthma
- Dr. Chris Fanta
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30. Non-pharmacological treatments for asthma
- Prof. Neil Thomson
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31. Asthma: beyond the prescription
- Prof. Martyn Partridge
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32. New drugs for asthma
- Prof. Peter Barnes
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33. Anti-IgE therapy for asthma
- Dr. Andrew Menzies-Gow
- Archived Lectures *These may not cover the latest advances in the field
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34. New drugs for asthma
- Prof. Peter Barnes
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35. Asthma phenotypes in children
- Prof. Andrew Bush
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36. Steroid resistance in asthma: mechanisms and potential therapies
- Prof. Ian Adcock
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37. Severe asthma in children
- Prof. Andrew Bush
Printable Handouts
Navigable Slide Index
- Introduction
- Outline
- Case history - chief complaint
- Case history - recent history
- Case history - physical exam
- Case history - initial treatment
- Outline - prevention
- The best management is prevention
- Preventive strategies
- Traffic-light model: green/yellow/red zones
- Peak flow meter with adjustable markers
- Asthma action plan - example
- Outline - assessment
- Patient assessment
- Risk factors for severe, potentially fatal asthma
- Physical findings in severe asthma attacks
- Lung function measurements
- Chest X-ray is of limited value
- Role of arterial blood gases
- Lung function & PCO2 in acute, severe asthma
- Outline - treatment
- Treatment of acute asthma - overview
- Principles of care for acute asthma
- Initial treatment - comparison of three regimens
- Initial treatment
- MDI and nebulizer equivalence
- MDI with spacer vs. nebulizer in severe disease
- Inhaled beta-agonists in acute asthma
- Patterns of response to albuterol
- Additional bronchodilators in acute, severe asthma
- Intravenous magnesium - meta-analysis
- Intravenous magnesium - randomized trial
- Helium-oxygen mixture (Heliox) (1)
- Helium-oxygen mixture (Heliox) (2)
- Helium-oxygen mixture (Heliox) (3)
- Bronchodilator failure - probable causes
- Steroids in acute, severe asthma
- Systemic steroids during hospitalization
- Oral steroids on emergency dept. (E.D.) discharge
- Intramuscular steroids on E.D. discharge
- Inhaled steroids following E.D. discharge (1)
- Inhaled steroids following E.D. discharge (2)
- Optimal dose of systemic steroids - unknown (1)
- Optimal dose of systemic steroids - unknown (2)
- Oral vs. intravenous corticosteroids
- Optimal duration of systemic steroids - unknown
- No need for oral steroid "taper"
- The outpatient "steroid burst"
- Antibiotics for acute, severe asthma
- Other therapies of unproven/unlikely benefit
- Outline - disposition
- Rationale for in-hospital treatment
- Indications for admission
- Unconventional therapies in acute, severe asthma
- Indications for intubation & mechanical ventilation
- Discharge criteria
- Patient education prior to hospital discharge
- Conclusions
- Summary
- Thank you
Topics Covered
- Asthma prevention, assessment, treatment and disposition
- Risk factors and physical findings in severe asthma attacks
- Treatments: Steroids, MDI, Nebulizer, Beta-agonists, Bronchodilators, Magnesium, Heliox & Antibiotics
- Unproven and unconventional therapies
- Rationale for in-hospital treatment and indications for admission
- Indications for intubation & mechanical ventilation
- Discharge criteria and patient education prior to hospital discharge
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
Fanta, C. (2013, January 24). Management of acute exacerbations of asthma [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 30, 2024, from https://doi.org/10.69645/UKAU9201.Export Citation (RIS)
Publication History
Financial Disclosures
- Dr. Chris Fanta has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.