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Printable Handouts
Navigable Slide Index
- Introduction
- Stem cells: revolution in medicine
- Organ regeneration - amphibians and mammals
- Translation in order of probable success
- Present results of clinical research
- Different types of multi-potential stem cells
- Novel problems in stem cell translational science
- Traditional pharmacology vs. stem cells repair
- Stem cells repair: the differences between organs
- Mechanism of efficacy
- Animal studies data - for and against stem cells
- Human studies data - for and against stem cells
- Lack of intellectual property
- Cardiac therapeutics: small molecules
- Gene therapy
- Stem cell therapy
- Doctors lead clinical development
- Confusion among regulators
- Interest among politicians: positive and negative
- Present situation
- Female heart transplanted to male:cell infiltration
- The clinical trials - routes of stem cells delivery
- Top Care - AMI studies - protocol
- Top Care study: results
- Top Care study: safety and clinical outcome
- Summary of data from three studies
- Plan for future clinical research
- Gene transfer to stem cells
- Conclusion
Topics Covered
- Amphibians and organ repair
- Application of different cell types to the heart in animal models
- Stem cell repair is complex
- The mechanism of efficacy is unknown
- Intellectual property in autologous stem cells
- Autologous bone marrow cells can cause an increase in ejection fraction after myocardial infarction
- Definitive randomised, controlled, blinded trials are needed
- Gene therapy plus stem cell therapy is the future
Talk Citation
Martin, J. (2007, October 1). Clinical potential of stem cells [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 7, 2024, from https://doi.org/10.69645/LZOU3066.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. John Martin has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.