Bacterial biomarkers

Published on September 27, 2012   71 min

A selection of talks on Cell Biology

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Welcome to Henry Stewart presentation on bacterial biomarkers. Thanks to the organizers of this series for the opportunity to talk to you about the current state of the art research and clinical applications of biomarkers for bacterial detection, identification, and monitoring. My name is Christiane Honisch. I started my career in infectious disease biomarker research and the development of novel methods for microbial detection and monitoring in 1999, with a PhD in Molecular Biology and Microbiology from the Technical University, Carolo-Wilhelmina zu Braunschweig in Germany. My research was focused on the discovery of genomic and proteomic markers for the detection of pathogenic mycobacteria, mainly mycobacterium tuberculosis; the infectious agent for tuberculosis. Continued interest in Nucleic Acids Research and Novel technologies led to the past 11 years in industry developing mass spectrometry applications for the detection and monitoring of nucleic acid-based bacterial and viral biomarkers. Public health institutions worldwide like the Health Protection Agency in London in the UK, and the Center of Disease Control and Prevention in Atlanta, Georgia in the US embrace this Genome technology. My current research interests at the University of California, San Diego continues to be focused on microbial biomarkers and mass spectrometry, now in microbial communities.
The following presentation will provide a general overview of bacterial biomarkers especially of infectious disease agents combined with an overview on developments of technology for example mass spectrometry for the detection and monitoring of microorganisms.