• General Strategies in Biomarker Research
• 55 min
  1. The proteomic revolution

  • Dr. Larry Gold
• 39 min
  2. Lipid biomarkers: lipidomics of the macrophage and plasma lipidomes

  • Prof. Edward A. Dennis
• New Tools for Biomarker Research
• 38 min
  3. The future of CNVs: sequence based resolution and links to human disease 1

  • Prof. Evan Eichler
• 31 min
  4. The future of CNVs: sequence based resolution and links to human disease 2

  • Prof. Evan Eichler
• 59 min
  5. Development of glyco-biomarkers using glycoproteomics technologies

  • Dr. Hisashi Narimatsu
• 32 min
  6. Circulating nucleic acids as biomarkers in cancer patients

  • Prof. Klaus Pantel
• Specific Disease Applications
• 28 min
  7. Biomarkers in breast cancer

  • Prof. Joe Duffy
• 71 min
  8. Bacterial biomarkers

  • Dr. Christiane Honisch
• 32 min
  9. Diabetes biomarkers

  • Prof. Naveed Sattar
• 60 min
  10. Gene networks, brain networks: understanding schizophrenia

  • Dr. Daniel Weinberger
• 29 min
  11. Biomarkers for Huntington's disease - promises and challenges

  • Prof. Sarah Tabrizi
• 31 min
  12. Update on fluid biomarkers for neurodegenerative diseases

  • Prof. Henrik Zetterberg
• 31 min
  13. Biomarkers in osteoarthritis

  • Dr. Ali Mobasheri
• Biomarkers in Drug Discovery and Delivery
• 31 min
  14. Pharmacogenomics: emphasis on clinical drug development

  • Dr. Amelia Warner
• 25 min
  15. Biomarkers in drug development: potential use and challenges

  • Dr. Abdel-Bassett Halim
• 41 min
  16. Patient stratification for drug treatment in oncology and other diseases

  • Dr. Tim Harris
• Biomarkers in development, nutrition, and health
• 50 min
  17. Building genetic and environmental marker models to predict exceptional survival

  • Prof. Thomas Perls
• 29 min
  18. Ethnic differences in nutrition

  • Prof. Jose Ordovas
• 55 min
  19. Non-invasive prenatal diagnostics

  • Prof. Y. M. Dennis Lo
• 44 min
  20. Epigenetic biomarkers in cancer

  • Prof. Bob Brown
• Archived Lectures *These may not cover the latest advances in the field
• 23 min
  21. Biomarkers for Alzheimer's disease

  • Prof. Henrik Zetterberg

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Overview
3. LIPID MAPS
4. LIPID MAPS cores and bridges
5. CLASS
6. Kdo2-Lipid A
7. Macrophage lipid metabolism
8. Sterol biosynthesis pathway
9. Lipidomics components
10. www.lipidmaps.org
11. PLA2 function in arachidonic acid release
12. Eicosanoid signaling pathways in macrophage
13. Basic macrophage experimental scheme
14. Cellular eicosanoid metabolism (1)
15. Cellular eicosanoid metabolism (2)
16. KLA treatment in RAW macrophage
17. Fluxomics model for KLA treatment
18. Cellular eicosanoid metabolism (3)
19. Cellular eicosanoid metabolism (4)
20. Macrophage phenotypes
21. Eicosanoid changes by phenotype
22. COX-2 metabolites and transcripts
23. PGE2/PGD2 vs. PGES/PGDS transcripts
24. Proportionality of eicosanoids and transcripts
25. Directed proteomics on enzymes
26. Protein abundance after KLA stimulation
27. Eicosanoid genes to proteins to metabolites
28. Human plasma lipidomics
29. Human plasma metabolites
30. Human plasma lipid categories
31. Prostaglandins in the human plasma
32. Sterols in the human plasma
33. Human plasma lipid diversity
34. Plasma lipids in the metabolic syndrome
35. Acknowledgments
36. The LIPID MAPS consortium
37. Concluding remarks

Topics Covered

• The LIPID MAPS initiative
• Relating LIPID MAPS to genomics, proteomics and metabolomics
• Lipidomics analysis
• Eicosanoid metabolism in macrophages
• Lipidomics analysis of human plasma

Links

Series:

• Biomarkers

Categories:

• Biochemistry
• Cell Biology
• Immunology

Therapeutic Areas:

• Immunology & Inflammation

Talk Citation

Publication History

• Published on September 27, 2012

Financial Disclosures

• Prof. Edward A. Dennis has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.