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Navigable Slide Index

1. Introduction
2. Overview
3. LIPID MAPS
4. LIPID MAPS cores and bridges
5. CLASS
6. Kdo2-Lipid A
7. Macrophage lipid metabolism
8. Sterol biosynthesis pathway
9. Lipidomics components
10. www.lipidmaps.org
11. PLA2 function in arachidonic acid release
12. Eicosanoid signaling pathways in macrophage
13. Basic macrophage experimental scheme
14. Cellular eicosanoid metabolism (1)
15. Cellular eicosanoid metabolism (2)
16. KLA treatment in RAW macrophage
17. Fluxomics model for KLA treatment
18. Cellular eicosanoid metabolism (3)
19. Cellular eicosanoid metabolism (4)
20. Macrophage phenotypes
21. Eicosanoid changes by phenotype
22. COX-2 metabolites and transcripts
23. PGE2/PGD2 vs. PGES/PGDS transcripts
24. Proportionality of eicosanoids and transcripts
25. Directed proteomics on enzymes
26. Protein abundance after KLA stimulation
27. Eicosanoid genes to proteins to metabolites
28. Human plasma lipidomics
29. Human plasma metabolites
30. Human plasma lipid categories
31. Prostaglandins in the human plasma
32. Sterols in the human plasma
33. Human plasma lipid diversity
34. Plasma lipids in the metabolic syndrome
35. Acknowledgments
36. The LIPID MAPS consortium
37. Concluding remarks

Topics Covered

• The LIPID MAPS initiative
• Relating LIPID MAPS to genomics, proteomics and metabolomics
• Lipidomics analysis
• Eicosanoid metabolism in macrophages
• Lipidomics analysis of human plasma

Links

Series:

• Biomarkers

Categories:

• Biochemistry
• Cell Biology
• Immunology

Therapeutic Areas:

• Immunology & Inflammation

Talk Citation

Dennis, E.A. (2012, September 27). Lipid biomarkers: lipidomics of the macrophage and plasma lipidomes [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved November 21, 2024, from https://doi.org/10.69645/GJIM9382.
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Publication History

• Published on September 27, 2012

Financial Disclosures

• Prof. Edward A. Dennis has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.