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- Epidemiology and risk factors
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1. Epidemiology of COPD
- Dr. David Mannino
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2. COPD in never smokers
- Dr. Sundeep Salvi
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3. Genetics of chronic obstructive pulmonary disease (COPD)
- Prof. Martin Tobin
- Phenotypes of COPD
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4. COPD and asthma: similarities and differences
- Prof. Peter Barnes
- Pathophysiology and mechanisms of COPD
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5. The pathology of chronic obstructive pulmonary disease
- Prof. James Hogg
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6. The continuum of COPD: a physiological perspective
- Prof. Denis O'Donnell
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7. Inflammatory and immune mechanisms in COPD
- Prof. Peter Barnes
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8. Mechanisms of COPD exacerbations and relation to exacerbation therapy
- Prof. Wisia Wedzicha
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9. Protease-antiprotease balance
- Prof. Robert Stockley
- Therapy and management
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10. Updates in chronic obstructive pulmonary disease (COPD)
- Dr. Omar S. Usmani
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11. Long-acting bronchodilators in COPD
- Prof. Bart Celli
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12. Treatment of COPD exacerbations
- Prof. Antonio Anzueto
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13. Pulmonary rehabilitation: history, promise and problems
- Prof. Richard Casaburi
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14. Lung volume reduction: advances in COPD
- Dr. Nick Hopkinson
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15. New pharmacological therapies for COPD
- Prof. Peter Barnes
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16. The Salford lung study in COPD
- Dr. Dave Leather
- COPD case studies
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17. COPD treatment case I: COPD with “bronchitis attacks”
- Dr. Janwillem Kocks
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18. COPD treatment case II: COPD with asthma as child
- Dr. Janwillem Kocks
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19. COPD treatment case III: COPD with pre-diabetes
- Dr. Janwillem Kocks
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20. Tailoring care for advanced COPD
- Prof. Wissam Chatila
- Archived Lectures *These may not cover the latest advances in the field
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21. Alpha-1 antitrypsin deficiency: state of the art
- Dr. Jamie Stoller
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22. Oxidative stress in COPD
- Prof. William MacNee
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23. Managing co-morbidity in COPD
- Dr. John Hurst
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24. Clinical phenotypes of COPD
- Prof. Jørgen Vestbo
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25. Pulmonary rehabilitation: focusing on rehabilitative exercise
- Prof. Richard Casaburi
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26. Genetics of COPD
- Prof. Ian Hall
Printable Handouts
Navigable Slide Index
- Introduction
- Outline
- FEV1 decline and disability
- Decline of FEV1 in COPD
- Symptomatic COPD: natural history?
- New evidence
- Physical activity in COPD
- Health-related quality of life scores
- A question arises
- Inflammation in the early stages of COPD
- Small-airway obstruction and emphysema
- Pathophysiology of mild COPD
- Mechanisms of air trapping (1)
- Cross-sectional study
- Natural history of lung hyperinflation in COPD
- COPD challenge test
- Cardiopulmonary exercise testing
- Exertional dyspnea intensity
- Exercise responses in symptomatic COPD
- Ventilatory response to exercise
- Ventilation-perfusion imbalance in COPD
- Operating lung volumes during exercise
- The importance of dynamic lung hyperinflation
- Respiratory mechanical measurements
- Esophageal pressure and flow tracings
- Respiratory muscle pressures during exercise (1)
- The continuum of COPD
- Respiratory muscle pressures during exercise (2)
- Dyspnea with increasing COPD severity
- Intensity and quality of dyspnea
- Progressive neuromechanical dissociation
- Operating lung volumes during exercise (1)
- Sensory-mechanical relations during exercise (1)
- Sensory-mechanical relations during exercise (2)
- Respiratory mechanics at the limits of tolerance
- Evolution of dyspnea during exercise in COPD
- Neuromechanical coupling and dissociation
- Conclusions (1)
- Conclusions (2)
- Improving dyspnea and activity restriction
- Pharmacological volume reduction
- Lung hyperinflation and its reversibility
- Bronchodilator responsiveness
- Mechanisms of air trapping (2)
- Pulmonary function post ipratropium bromide
- Impact of acute anticholinergic therapy
- Mechanical measurements during exercise
- Operating lung volumes during exercise (2)
- Effects of lung volume deflation
- IC response to long-acting bronchodilators
- Improvements in respiratory mechanics
- Responses to bronchodilators in COPD
- Conclusions (3)
- Clinical course of COPD (1)
- Clinical course of COPD (2)
Topics Covered
- Evolution of respiratory impairments from mild to sever COPD
- Progression of the symptoms of COPD: dyspnea and exercise impairment
- Mechanism s of progression
- Optimizing respiratory mechanics
Links
Series:
Categories:
Therapeutic Areas:
Talk Citation
O'Donnell, D. (2012, July 31). The continuum of COPD: a physiological perspective [Video file]. In The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved December 30, 2024, from https://doi.org/10.69645/KDWY9261.Export Citation (RIS)
Publication History
Financial Disclosures
- Prof. Denis O'Donnell has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.