• View the Talks
• 42 min
  1. Historic introduction to innate immunity

  • Prof. Heiko Herwald
  • Prof. Arne Egesten
• 52 min
  2. Evolution of innate immunity

  • Prof. Jim Kaufman
• 25 min
  3. The phagocytic synapse in distinguishing particulate and soluble stimuli

  • Prof. David Underhill
• 23 min
  4. How bacterial pathogens avoid phagocyte killing

  • Dr. Thomas Areschoug
• 43 min
  5. Origin of myeloid cells

  • Prof. Frederick A. Geissmann
• 67 min
  6. Dendritic cells

  • Prof. Muriel Moser
• 38 min
  7. Eosinophil biology and disorders associated with eosinophilia

  • Dr. Thomas B. Nutman
• 60 min
  8. CD1d-restricted NKT cells: regulators of inflammation and autoimmunity

  • Prof. Steven A. Porcelli
• 50 min
  9. Innate-like B cells

  • Prof. John F. Kearney
• 58 min
  10. Cytoplasmic innate immune sensors

  • Prof. Seth Masters
• 76 min
  11. An introduction to the interleukin-1 family of cytokines

  • Dr. John Sims
• 28 min
  12. The role of myeloid cells in HIV associated immune reconstitution inflammatory syndrome

  • Prof. Robert Wilkinson
  • Prof. Graeme Meintjes
• 37 min
  13. Antimicrobial peptides in the innate immune system of the lung

  • Prof. Dr. Pieter S. Hiemstra
• 49 min
  14. Chemokines and their receptors: their biology and therapeutic relevance

  • Dr. Amanda Proudfoot
• 45 min
  15. Heat shock proteins and their role in the immune regulation of inflammation

  • Prof. Willem Van Eden
• 42 min
  16. Tissue damage control confers host tolerance to infection

  • Dr. Miguel P. Soares
• 22 min
  17. Autophagy as a barrier to infection

  • Prof. Michele Swanson
• 42 min
  18. Innate immunity in the intestine in health and disease

  • Prof. Kevin Maloy
• 51 min
  19. Dendritic cells and the eye: their role in the ocular immune response

  • Prof. John V. Forrester
• 26 min
  20. Mononuclear phagocytes and HIV infection

  • Dr. Guido Poli
• 41 min
  21. Th17 cells and innate immunity

  • Prof. Mihai Netea
• 37 min
  22. Epigenetic regulation of innate immunity

  • Dr. Osamu Takeuchi
• 66 min
  23. Intracellular DNA sensing pathways

  • Prof. Veit Hornung
• 52 min
  24. Physiology of innate immunity

  • Prof. Keith W. Kelley
• 49 min
  25. Innate immunity in the genitourinary tract: genetics of susceptibility to disease or asymptomatic carriage

  • Prof. Catharina Svanborg
• 32 min
  26. Regulation of type 2 immunity by basophils

  • Prof. David Voehringer
• Archived Lectures *These may not cover the latest advances in the field
• 53 min
  27. TLRs, NLRs, DAMPs and PAMPs

  • Prof. Luke O'Neill

Printable Handouts

PDF

Navigable Slide Index

1. Introduction
2. Questions (1)
3. What are eosinophils? (1)
4. What are eosinophils? (2)
5. Eosinophil facts
6. The eosinophil
7. Tissue distribution of eosinophils in normal rats
8. Normal eosinophil morphology
9. Eosinophil electron micrograph
10. Eosinophil structure - primary granules
11. Eosinophil structure - secondary granules
12. Major Basic Protein (MBP)
13. Eosinophil Cationic Protein (ECP)
14. Eosinophil-Derived Neurotoxin (EDN)
15. Eosinophil Peroxidase (EPO)
16. Charcot-Leyden crystal protein
17. Charcot-Leyden crystals
18. Eosinophil secretion/degranulation
19. Eosinophil 'specific' granules
20. Eosinophils: surface components
21. Eosinophils: mediators
22. Eosinophil life cycle
23. Eosinophils differentiation and trafficking
24. Eosinophil moving from circulation into tissues
25. Eosinophil activation
26. Markedly activated eosinophil
27. Activated eosinophils have altered morphology
28. Questions (2)
29. Eosinophils: function
30. Eosinophil-mediated pathogenesis
31. Eosinophil: protective role against parasites
32. Eosinophil: pathogenic role in allergy
33. Eosinophils and apoptosis
34. Other functions?
35. Questions (3)
36. Eosinophilia
37. Eosinophilia: differential diagnosis
38. Eosinophilia and drug reactions
39. Eosinophilia and nonparasitic infectious diseases
40. Eosinophilia and protozoan infections
41. Eosinophilia and ectoparasites
42. Helminth causes of eosinophilia
43. Unexplained eosinophilia
44. Group of hypereosinophilic syndromes
45. Hypereosinophilic syndrome
46. HES subtypes
47. End-organ dysfunction in HES
48. HES: heart disease
49. FIP1L1/PDGFRA-associated CEL
50. Tissue fibrosis is a common sequela of F/P-HES
51. Familial eosinophilia
52. Summary
53. Acknowledgements

Topics Covered

• Eosinophil basics
• Eosinophil morphology
• Eosinophil function
• Eosinophil activation
• Eosinophilia
• Disorders associated with eosinophilia

Links

Series:

• Cells of the Innate Immune System

Categories:

• Biochemistry
• Cell Biology
• Clinical Practice
• Immunology

Therapeutic Areas:

• Immunology & Inflammation

Talk Citation

Publication History

• Published on June 11, 2012

Financial Disclosures

• Dr. Thomas B. Nutman has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.