Topics Covered
- Genomics of the TNF/TNFR superfamily
- TNF/TNFR signaling types
- Various domains of TNFR
- TNF ligands and receptor binding
- Fas and the TNFR family
- Apoptosis through DISC recruitment
- FAS-FADD crystal structure
- Gene expression through TRAF proteins and regulation by dynamic expression of ligands
- Lymph node development
- Innate immunity enhancement
- B & T cells and the TNFR superfamily
- Multiple programmed cell death pathways
- Osteoclast development
- Molecular mechanisms of genetic diseases and defects in the Fas pathway
- Fas intra and extracellular mutations
- Therapeutics and anti-inflammatory uses of TNF superfamily blockade
Links
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Talk Citation
Siegel, R. (2011, December 5). TNF superfamily cytokines and receptors in the healthy and diseased immune system [Video file]. In
The Biomedical & Life Sciences Collection, Henry Stewart Talks. Retrieved October 2, 2023, from
https://hstalks.com/bs/2150/.
Export Citation (RIS)
Publication History
-
Published on December 5, 2011
Financial Disclosures
- Dr. Richard Siegel has not informed HSTalks of any commercial/financial relationship that it is appropriate to disclose.